Evidence map›Paper›PMID 41332694›Full record

ArticlebioRxiv : the preprint server for biology2025

GABA-glutamate corelease is a mechanism for state-dependent neurotransmission.

Shelley M Warlow, Dina S Dowlat, Nick G Hollon, Lauren Faget, Lucie Oriol, Vivien Zell, Larry S Zweifel, Thomas S Hnasko

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shelley M WarlowDepartment of Psychological and Brain Sciences, Dartmouth College, New Hampshire, USA.ORCID 0000-0003-3926-7741
Dina S DowlatDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Nick G HollonDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Lauren FagetDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Lucie OriolDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Vivien ZellDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Larry S ZweifelDepartment of Pharmacology, University of Washington, Seattle, WA, USA.
Thomas S HnaskoDepartment of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

Funding

University of Washington Center of Excellence in Opioid Addiction ResearchP30DA048736 · NIDA · UNIVERSITY OF WASHINGTON · PI Michael R. Bruchas · 2019 to 2026
$13.0M
Role of novel VTA neurons in addiction-related behaviorsR01DA036612 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Thomas Hnasko · 2014 to 2026
$5.6M
Balancing motivation through VTA GABA/Glutamate co-transmissionR00MH130688 · NIMH · DARTMOUTH COLLEGE · PI Shelley May Warlow · 2024 to 2026
$747k
The role of VTA neurotransmitter co-release in health and diseaseF32MH122192 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WARLOW, SHELLEY MAY · 2019 to 2022
$178k
BLRD VA I01 BX005782NIDA NIH HHS P30 DA048736NIDA NIH HHS R01 DA036612NIMH NIH HHS F32 MH122192NIMH NIH HHS R00 MH130688
6 · The paper itself

Abstract

Ventral tegmental area neurons projecting to lateral habenula (LHb) corelease the main inhibitory and excitatory transmitters, GABA and glutamate (VTA

Identifiers

PMID41332694
PMCPMC12667897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.