Evidence map›Paper›PMID 41332634›Full record

ArticlebioRxiv : the preprint server for biology2025

Control of antigen presentation on MHC-I by a bacterial secretion system.

Owen Leddy, Rachel McGinn, Benjamin Allsup, Madison Leone, Penny Timms, Matias Gutierrez-Gonzalez, Ahmed S Fahad, Ryan Milligan, Wilfredo F Garcia-Beltran, Brandon J DeKosky and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Owen LeddyDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.
Rachel McGinnDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.
Benjamin AllsupDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.
Madison LeoneRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Penny TimmsRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Matias Gutierrez-GonzalezRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Ahmed S FahadRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Ryan MilliganDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.
Wilfredo F Garcia-BeltranRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Brandon J DeKoskyRagon Institute of MGH, Harvard, and MIT, Cambridge MA USA.
Forest M WhiteDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.
Bryan D BrysonDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge MA USA.ORCID 0000-0003-1716-6712

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
TRAINING GRANTS IN ENVIROMENTAL TOXICOLOGYT32ES007020 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ESSIGMANN, JOHN M · 1985 to 2024
$13.1M
Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieuU54CA283114 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Forest M White · 2023 to 2026
$9.7M
High-dimensional characterization of phagosome composition, control and phagocytic receptor redundancyR35GM142900 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI BRYSON, BRYAN DAVID · 2021 to 2025
$2.1M
Identification of adaptive response mechanisms in breast cancer by information theory and proteomicsU01CA238720 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KRAVCHENKO-BALASHA, NATALY, WHITE, FOREST M · 2019 to 2023
$2.0M
NCI NIH HHS U01 CA238720NCI NIH HHS U54 CA283114NIAID NIH HHS P30 AI060354NIEHS NIH HHS T32 ES007020NIGMS NIH HHS R35 GM142900
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41332634
PMCPMC12667757

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.