Evidence map›Paper›PMID 41332606›Full record

ArticlebioRxiv : the preprint server for biology2025

Ku limits aberrant mRNA splicing promoted by intronic antisense Alu elements.

Giovanni Pascarella, Mariia Mikhova, Gargi Parkhi, Jared Godfrey, Joshua Heyza, Tomáš Janovič, Andrew Olive, Piero Carninci, Jens C Schmidt, Katheryn Meek

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanni PascarellaRIKEN Center for Integrative Medical Sciences (IMS), Yokohama Japan.ORCID 0000-0002-9225-0458
Mariia MikhovaDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, U.S.A.
Gargi ParkhiDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI 48824, U.S.A.
Jared GodfreyDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI 48824, U.S.A.
Joshua HeyzaInstitute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, MI, U.S.A.
Tomáš JanovičInstitute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, MI, U.S.A.
Andrew OliveDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI 48824, U.S.A.
Piero CarninciRIKEN Center for Integrative Medical Sciences (IMS), Yokohama Japan.ORCID 0000-0001-7202-7243
Jens C SchmidtInstitute for Quantitative Health Sciences and Engineering, Michigan State University, East Lansing, MI, U.S.A.ORCID 0000-0001-9061-7853
Katheryn MeekDepartment of Microbiology, Genetics, & Immunology, Michigan State University, East Lansing, MI 48824, U.S.A.ORCID 0000-0002-0454-4414

Funding

Relevant Targets of the DNA Dependent Protein KinaseR01AI048758 · NIAID · MICHIGAN STATE UNIVERSITY · PI MEEK, KATHERYN D · 2000 to 2016
$5.2M
Single-molecule Analysis of the DNA Damage Response in Living CellsDP2GM142307 · NIGMS · MICHIGAN STATE UNIVERSITY · PI SCHMIDT, JENS CHRISTOPHER · 2020 to 2020
$2.1M
Defining the mechanistic basis of ATM’s impact on VDJ recombinationR01AI147634 · NIAID · MICHIGAN STATE UNIVERSITY · PI MEEK, KATHERYN D, YU, KEFEI · 2019 to 2024
$1.9M
NIAID NIH HHS R01 AI048758NIAID NIH HHS R01 AI147634NIGMS NIH HHS DP2 GM142307
6 · The paper itself

Abstract

Alu elements are short repeats that occupy approximately 10% of the human genome

Identifiers

PMID41332606
PMCPMC12667784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.