Evidence map›Paper›PMID 41332367›Full record

ArticleHistology and histopathology2026

1,25-Dihydroxyvitamin D3 mitigates high glucose-induced oxidative stress, inflammation, and extracellular matrix accumulation in glomerular mesangial cells via the ROS/TXNIP/NLRP3 pathway.

Qingyue Meng, Bo Chen, Chunjiang Zhang, Lin Jia, Xingyu Yao, Gang Liu

Abstract read
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Article in Histology and histopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qingyue MengDepartment of Nephrology, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Bo ChenDepartment of Pediatrics, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Chunjiang ZhangDepartment of Nephrology, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Lin JiaDepartment of Nephrology, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Xingyu YaoDepartment of Pediatrics, The First Affiliated Hospital of Shihezi University, Shihezi, China.
Gang LiuDepartment of Nephrology, The First Affiliated Hospital of Shihezi University, Shihezi, China. 1269297273@hotmail.com.

Funding

Bingtuan Science and Technology Program 2024ZD047
6 · The paper itself

Abstract

background1,25-Dihydroxyvitamin D3 (1,25(OH)

methodsDN was induced in Wistar rats via high-fat diet (4 weeks) and streptozotocin injection (30 mg/kg, i.p.); hyperglycemic rats were randomized into DN and DN + 1,25(OH)

results1,25(OH)

conclusion1,25(OH)

Indexed as

CalcitriolDiabetic NephropathiesExtracellular MatrixMesangial CellsNLR Family, Pyrin Domain-Containing 3 ProteinOxidative StressAnimalsCarrier ProteinsCell Cycle ProteinsDiabetes Mellitus, ExperimentalGlucoseInflammasomesInflammationMaleRatsRats, WistarCalcitriolCarrier ProteinsCell Cycle ProteinsGlucoseInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratReactive Oxygen SpeciesThioredoxinsTXNIP protein, rat

Identifiers

PMID41332367

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.