Evidence map›Paper›PMID 41332296›Full record

ArticleScandinavian journal of psychology2026

The Moderating Role of Psychological Well-Being in the Relation Between Stressful Life Events and Common Mental Disorders in the General Population.

Peter M Ten Klooster, Margreet Ten Have, Annemarie I Luik, Marlous Tuithof, Ernst T Bohlmeijer

Abstract read
In one paragraph

Article in Scandinavian journal of psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter M Ten KloosterDepartment of Technology, Human and Institutional Behaviour, University of Twente, Enschede, the Netherlands.ORCID https://orcid.org/0000-0002-2565-5439
Margreet Ten HaveNetherlands Institute of Mental Health and Addiction (Trimbos Institute), Utrecht, the Netherlands.ORCID https://orcid.org/0000-0003-0086-2199
Annemarie I LuikNetherlands Institute of Mental Health and Addiction (Trimbos Institute), Utrecht, the Netherlands.ORCID https://orcid.org/0000-0001-7517-197X
Marlous TuithofNetherlands Institute of Mental Health and Addiction (Trimbos Institute), Utrecht, the Netherlands.ORCID https://orcid.org/0000-0002-5802-3913
Ernst T BohlmeijerDepartment of Technology, Human and Institutional Behaviour, University of Twente, Enschede, the Netherlands.ORCID https://orcid.org/0000-0002-7861-1245

Funding

Ministerie van Volksgezondheid, Welzijn en Sport
6 · The paper itself

Abstract

Stressful life events (SLEs) are known to be associated with an increased prevalence of common mental disorders (CMDs), but the potential moderating role of psychological well-being has not been comprehensively studied. In total, 6194 adults aged 18-75 years were interviewed for the third Netherlands Mental Health Survey and Incidence Study (NEMESIS-3). Assessments included the adapted Composite International Diagnostic Interview (CIDI v3.0) to determine DSM-5 mood, anxiety and substance use disorders, Brugha's List of Threatening Experiences for SLEs, and Brief INSPIRE-O for psychological well-being. Logistic regressions tested associations between having experienced at least two SLEs and the different CMDs and additive interactions with psychological well-being. Having experienced ≥ 2 SLEs in the last year was associated with a higher prevalence of all CMDs in the last year, with adjusted odds ratios ranging from 1.71 (95% CI: 1.39; 2.10) for substance use disorders to 3.43 (95% CI: 2.73; 4.30) for mood disorders. The interaction effect of ≥ 2 SLEs and low psychological well-being was statistically significant for any CMD (RERI = 5.64, 95% CI: 3.18; 8.10), mood disorder (RERI = 23.09, 95% CI: 10.10; 36.10) and anxiety disorder (RERI = 3.45, 95% CI: 1.27; 5.63), but not for substance use disorder (RERI = 0.21, 95% CI: -1.38; 1.80). The joint presence of ≥ 2 SLEs and poor psychological well-being was associated with a higher prevalence of mood and anxiety disorders than would be expected from the sum of their individual associations. Promoting psychological well-being may be a fruitful public mental health strategy to increase resilience against SLEs.

Indexed as

Anxiety DisordersLife Change EventsMental DisordersMental HealthMood DisordersStress, PsychologicalSubstance-Related DisordersAdolescentAdultAgedFemaleHumansMaleMiddle AgedNetherlandsPrevalencemental disorderspopulation healthpsychological well‐beingrisk factorsstressful events

Identifiers

PMID41332296
PMCPMC12984009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.