Evidence map›Paper›PMID 41332245›Full record

ArticleFuture cardiology2025

Plasma expression of lncRNA Wisper in patients with heart failure and patients with myocardial infarction.

Jordanka G Doneva, Veselin D Valkov, Ivan S Donev, Atanas A Atanasov, Zafer A Sabit, Ivo N Sirakov, Yavor K Kashlov, Lylia I Stoyanova, Radka T Hadjiolova

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Article in Future cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jordanka G DonevaDepartment of Propedeutics of Internal Medicine, Medical University of Varna, Varna, Bulgaria.
Veselin D ValkovDepartment of Propedeutics of Internal Medicine, Medical University of Varna, Varna, Bulgaria.
Ivan S DonevClinic of Medical Oncology, MHAT "Nadezhda", Sofia, Bulgaria.
Atanas A AtanasovDepartment of Cardiology, St. Marina UMHAT, Varna, Bulgaria.
Zafer A SabitDepartment of Physiology and Pathophysiology, Medical Faculty, Medical University-Sofia, Sofia, Bulgaria.
Ivo N SirakovDepartment of Medical Microbiology, 'Corr. Prof. Ivan Mitov, MD, DMSc', Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria.
Yavor K KashlovDepartment of Propedeutics of Internal Medicine, Medical University of Varna, Varna, Bulgaria.
Lylia I StoyanovaDepartment of Propedeutics of Internal Medicine, Medical University of Varna, Varna, Bulgaria.
Radka T HadjiolovaDepartment of Physiology and Pathophysiology, Medical Faculty, Medical University-Sofia, Sofia, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure (HF) and ST-elevation myocardial infarction (STEMI) are the major causes of morbidity and mortality worldwide. Recent evidence indicates that long noncoding RNAs (lncRNAs) participate in cardiac fibrosis, which develops to varying degrees in these conditions. PATIENTS AND

methodsThis retrospective study analyzed the plasma expression levels of lncRNA Wisper using RT-qPCR in 28 patients with HF (NYHA class III - IV, reduced ejection fraction), 37 patients with STEMI, and 15 healthy controls. Diagnostic accuracy was assessed using receiver operating characteristic (ROC) curve analysis, and correlations with clinical parameters were evaluated. RESULTS AND

conclusionsPatients with HF and STEMI showed significantly higher plasma Wisper expression than that of controls (

Indexed as

Heart FailureMyocardial InfarctionRNA, Long NoncodingST Elevation Myocardial InfarctionAgedBiomarkersFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveBiomarkersRNA, Long Noncodingcardiovascularheart failureLong-non coding RNA (lncRnas)markermyocardial injury

Identifiers

PMID41332245
PMCPMC12758281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.