The use of Pretiva™ negative pressure therapy provides benefits in the management of hard-to-heal chronic wounds: A case series.

introduction and importanceChronic wounds pose a major global health challenge, often leading to prolonged disability, increased healthcare costs, and significant patient suffering. Conventional therapies frequently fail to achieve complete healing in complex cases, highlighting the need for innovative, cost-effective solutions. Portable negative pressure wound therapy devices (NPWT), offer new opportunities to enhance wound healing, particularly in emerging healthcare systems. CASE PRESENTATION: We report two cases of patients with hard-to-heal lower limb wounds. The first case involved a 48-year-old male with a chronic venous ulcer and repeated soft tissue infections. The second case involved a 52-year-old female with a chronic post-traumatic wound unresponsive to multiple surgical interventions. Both patients demonstrated significant clinical improvement following the application of Pretiva™ NPWT, including tissue regeneration, reduction of wound area, absence of exudate and odor, and decreased risk of limb loss. CLINICAL DISCUSSION: These cases illustrate how NPWT effectively reactivated healing in wounds that had stagnated under conventional care. The therapy's mechanisms enhancing microcirculation, reducing edema, and promoting granulation tissue formation, translated into rapid, clinically meaningful outcomes. The portability and ease of use of NPWT also support its feasibility in outpatient and resource-limited settings, addressing key gaps in chronic wound management in emerging countries.

conclusionThis case series illustrates the potential therapeutic value of Pretiva™ NPWT in the management of hard-to-heal chronic wounds. Its observed effectiveness and practical feasibility in outpatient and resource-constrained settings suggest it may be a valuable option in similar clinical contexts.