Evidence map›Paper›PMID 41331743›Full record

ArticleGlia2026

AMPA Receptors in NG2 Glia Differently Affect Signal Transduction in the Hippocampus and Cerebellum.

Dario Tascio, Nehal Gebril, Ronald Jabs, Christian Henneberger, Christian Steinhäuser, Gerald Seifert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Glia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dario TascioInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.ORCID 0009-0004-0755-4476
Nehal GebrilInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.
Ronald JabsInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.
Christian HennebergerInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.
Christian SteinhäuserInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.ORCID 0000-0003-2579-8357
Gerald SeifertInstitute of Cellular Neurosciences I, Medical Faculty, University of Bonn, Bonn, Germany.ORCID 0000-0003-1249-9083

Funding

Deutsche Forschungsgemeinschaft SE 774/6Deutsche Forschungsgemeinschaft STE 552/5
6 · The paper itself

Abstract

Gray matter NG2 glia constitute a heterogeneous population of cells whose functions remain incompletely understood. In the hippocampus, Schaffer collaterals activate AMPA receptors (AMPARs) in NG2 glia, giving rise to small excitatory post-synaptic currents (EPSCs). Climbing fibers of the cerebellum also form synapses with NG2 glia, although producing much larger EPSCs. We aimed to identify mechanisms generating these regional differences in the efficacy of neuron-glia synapses. Combined patch-clamp and RT-PCR analyses allowed for determining structural and functional differences of AMPARs expressed by the glial cells. Comparing pharmacological and molecular data in both regions revealed stronger expression of Ca

Indexed as

CerebellumHippocampusNeurogliaReceptors, AMPASignal TransductionAnimalsAntigensChondroitin Sulfate Proteoglycan 4Excitatory Postsynaptic PotentialsMaleMiceMice, Inbred C57BLPatch-Clamp TechniquesProteoglycansRatsSynapsesAntigensChondroitin Sulfate Proteoglycan 4ProteoglycansReceptors, AMPAAMPA receptorcerebellumhippocampusNG2 gliapatch clampsubunit composition

Identifiers

PMID41331743
PMCPMC12672973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.