Evidence map›Paper›PMID 41331714›Full record

ArticleAnnals of dermatology2025

Dynamic Evaluation of Glabellar Area Muscles Movement and Skin Displacement Using 3D Skin Displacement Vector Analysis.

Hyoung-Jin Moon, Jeong-Mok Cho, Sang-Eun Lee

Abstract read
In one paragraph

Article in Annals of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Hyoung-Jin MoonHugel Inc., Chuncheon, Korea.ORCID https://orcid.org/0000-0001-5236-6328
Jeong-Mok ChoEtonne Plastic Surgery Clinic, Seoul, Korea.ORCID https://orcid.org/0000-0003-4215-2427
Sang-Eun LeeDepartment of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. jennifer823@yuhs.ac.ORCID https://orcid.org/0000-0003-4720-9955

Funding

Hugel
6 · The paper itself

Abstract

backgroundThree-dimensional (3D) skin displacement vector analysis method provides a deeper understanding of dynamic muscle anatomy. Understanding the dynamic muscle anatomy in the glabellar area during frowning can facilitate safer and effective botulinum toxin injections for treating glabellar wrinkles.

objectiveWe aimed to investigate the skin displacement patterns of the glabellar area and adjacent skin during contraction of the glabellar muscles using 3D skin vector displacement analysis.

methodsTwenty-nine healthy individuals (26 female, 3 male; median age 40.5 years) participated in the study. Photographs of the face were taken at rest and during maximal contraction of the glabellar muscles. Each expression image was aligned to its respective static image to compute the differences in the skin position.

resultsTwo skin displacement patterns were identified during frowning: lateral pattern (89.66%), in which main skin vector displacement located on the eyebrow area and central pattern (10.34%), in which skin vector displacement mostly located between eyebrows. 62.07% showed asymmetric skin displacement. Analysis of the glabellar patterns showed that the 'U', '11', 'X', and 'π' patterns were observed in 38%, 38%, 14%, and 10% of cases, respectively, with corresponding skin vector displacement angles of 48°, 32°, 74°, and 24°. Additionally, 20.69% of subjects exhibited upward skin movement in the medial frontalis area during frowning. In 48% of subjects, the lateral and inferior portions of the orbicularis oculi muscle contracted, along with the upper medial portion.

conclusionThis data will serve as an important guide for Botulinum Toxin treatment of glabella wrinkles in Korean patients.

Indexed as

Biomechanical phenomenaBotulinum toxinsFacial musclesMuscle contractionSkin

Identifiers

PMID41331714
PMCPMC12715876

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