Evidence map›Paper›PMID 41331699›Full record

ArticleJournal of periodontology2026

Evaluation of Discoidin domain receptor 1 (DDR1) in junctional epithelial permeability and wound healing.

Christina Zachariadou, Anuja Doshi, Dimitris N Tatakis, Brian L Foster

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina ZachariadouDepartment of Periodontics and Endodontics, School of Dental Medicine, University at Buffalo, Buffalo, New York, USA.
Anuja DoshiDepartment of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada.
Dimitris N TatakisDepartment of Periodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Brian L FosterDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.

Funding

Functions of extracellular matrix proteins in dental and skeletal mineralizationR01DE027639 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2019 to 2026
$2.3M
NIDCR NIH HHS R01 DE027639NIDCR NIH HHS R01DE027639NIH HHS
6 · The paper itself

Abstract

backgroundEpithelium is the periodontal first line of defense against microbes. Discoidin domain receptor 1 (DDR1) is a collagen receptor expressed in epithelium. Ddr1 knockout (Ddr1

methodsEpithelium was analyzed in Ddr1

resultsNo differences in JE permeability were observed between Ddr1

conclusionsDDR1 does not affect JE permeability but may play a role in effective epithelial cell migration during cutaneous wound healing. PLAIN LANGUAGE SUMMARY: Epithelium is the periodontal first line of defense against microbial attacks. Discoidin domain receptor 1 (DDR1) is a collagen receptor expressed at the epithelium. Mice not expressing the receptor (Ddr1

Indexed as

Discoidin Domain Receptor 1Epithelial AttachmentWound HealingAnimalsCadherinsCell MovementCollagen Type IVFluorescent DyesGingivaMaleMiceMice, Inbred C57BLMice, KnockoutPermeabilityCadherinsCollagen Type IVDdr1 protein, mouseDiscoidin Domain Receptor 1Fluorescent Dyescadherinscollagendiscoidin domain receptor 1epitheliumperiodontiumpermeabilitywound healing

Identifiers

PMID41331699
PMCPMC13001129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.