Evidence map›Paper›PMID 41331554›Full record

SynthesisBMC pediatrics2025

The association between birth weight/rapid weight gain and early menarche: a systematic review and meta-analysis based on cohort studies.

Changxiang Ye, Xuan Zhou, Fang Li, Chenyang Cui, Lizhang Chen, Tingting Wang

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changxiang Ye *Hunan Provincial Center for Disease Control and Prevention (Hunan Academy of Preventive Medicine), Changsha, 410153, Hunan Province, China.
Xuan Zhou *Center for Medical Research, The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, 410011, China.
Fang LiHunan Center for Evidence-based Medicine, Clinical Epidemiology Laboratory, The Second Xiangya Hospital, Central South University, 139 Renmin Middle Road, Furong District, Changsha City, Hunan Province , 410011, China. lifang_csu@csu.edu.cn.
Chenyang CuiDepartment of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Changsha, China. cuicy_1998@163.com.
Lizhang ChenDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Changsha, Hunan, 410078, China. liche4005@126.com.
Tingting WangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, 110 Xiangya Road, Changsha, Hunan, 410078, China. wangting91123@126.com.

Funding

the Scientific Research Launch Project for new employees of the Second Xiangya Hospital of Central South University QH20230224
6 · The paper itself

Abstract

objectivesEarly menarche affects the mental and physical health of girls, but the evidence of the association between birth weight/rapid weight gain and early menarche is inconsistent. We conduct this systematic review and meta-analysis to explore their relationship.

methodsWe systematically searched for studies published before September 16, 2023 in Pubmed, Embase, Web of Science, and Cochrane Library. Studies that explored the relationship between birth weight/rapid weight gain and early menarche were included in our study. Data for every included study was independently extracted and evaluated by two authors. Statistical analyses was performed by RevMan version 5.3 or R version 3.4.1.

resultsPeople with high birth weight had a reduced risk of early menarche (RR = 0.91, 95%CI: 0.84-0.98). Rapid weight gain was associated with an increased risk of early menarche (RR = 1.41, 95%CI:1.01-1.96). Sensitivity analysis supported the stability of the results.

conclusionsOur results showed that high birth weight was associated with a reduced risk of early menarche, the rapid weight gain was associated with an increased risk of early menarche. This indicated that monitoring birth weight and weight gain in early infancy may reduce the occurrence of early menarche.

Indexed as

Birth WeightMenarcheWeight GainChildCohort StudiesFemaleHumansBirth weightEarly menarcheEndocrinologyMeta-analysisRapid weight gain

Identifiers

PMID41331554
PMCPMC12781735

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.