Evidence map›Paper›PMID 41331457›Full record

Trial reportJournal of neuroengineering and rehabilitation2025

Effectiveness of myoelectric wearable orthoses for upper extremity functional recovery in spinal cord injury- a pilot study.

Ghaith J Androwis, Amanda Engler, Courtney Craven, Julie Eng, Alfonse Gaite, Sameer Rana, Salli AlRabadi, Juan Ramirez, Remy Salloum, Christian Alvarez and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ghaith J AndrowisCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA. gandrowis@kesslerfoundation.org.
Amanda EnglerCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Courtney CravenCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Julie EngCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Alfonse GaiteCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Sameer RanaCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Salli AlRabadiCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Juan RamirezCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Remy SalloumCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Christian AlvarezCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Michael WassefCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Mohammed HuzienCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.
Brittany SniderKessler Institute for Rehabilitation and Rutgers New Jersey Medical School Department of Physical Medicine and Rehabilitation and the Kessler Foundation, Newark, NJ, USA.
Steven KirshblumKessler Institute for Rehabilitation and Rutgers New Jersey Medical School Department of Physical Medicine and Rehabilitation and the Kessler Foundation, Newark, NJ, USA.
Guang H YueCenter for Mobility and Engineering Research at Kessler Foundation, West Orange, NJ, USA.

Funding

Department of Defense (DoD), Congressionally Directed Medical Research Programs W81XWH-18-1-0728
6 · The paper itself

Abstract

Spinal cord injury (SCI) can lead to severe upper extremity (UE) impairments, limiting activities of daily living (ADLs) and independence. The overall goal of this pilot study was to evaluate a myoelectric-powered wearable orthosis (MPWO, MyoPro, MyoMo Inc.) for improving handgrip strength and active range of motion (AROM) in persons with chronic incomplete SCI. Ten participants with chronic cervical iSCI (mean age 53 years, AIS B-D) were randomized into three groups: Clinic-only MPWO (n = 3), Home + Clinic MPWO (n = 4), or Control traditional occupational therapy (TOT), (n = 3). All groups received 18 training sessions over 6 weeks (3×/week, ~ 60 min/session). Outcome measures included handgrip AROM and maximal grip force, assessed before and after training. Participants in the MPWO groups demonstrated substantial improvements in handgrip AROM and strength compared to baseline. On the MPWO-trained side, average increases of ~ 30-37% were observed in maximum handgrip AROM and ~ 28-30% in maximum grip force after training. The Home + Clinic MPWO group tended to exhibit the greatest gains. The non- MPWO trained (contralateral) side in the MPWO groups also showed indirect improvements, with modest increases of ~ 7-12% in AROM and grip force measures (suggesting a possible cross-education effect). In contrast, the TOT control group showed minimal changes (< 10% on average). These preliminary results indicate that UE-MPWO-assisted rehabilitation - especially when combined with at-home use - may enhance hand function in persons with chronic cervical SCI.

Indexed as

Orthotic DevicesRecovery of FunctionSpinal Cord InjuriesUpper ExtremityWearable Electronic DevicesActivities of Daily LivingAdultAgedFemaleHand StrengthHumansMaleMiddle AgedOccupational TherapyPilot ProjectsRange of Motion, ArticularActive range of motion.Myoelectric orthosisRehabilitationSpinal cord injuryUpper extremity

Identifiers

PMID41331457
PMCPMC12781642

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.