ArticleBMC ophthalmology2025
Differences in ocular surface parameters in patients with lacrimal duct obstruction at varying sites.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aims to explore the correlation between ocular surface parameters and the location of lacrimal duct obstruction.
methodsThis retrospective comparative study included 74 patients (94 eyes) diagnosed with lacrimal duct obstruction (LDO) between December 1, 2022, and October 1, 2024. Based on the obstruction site, affected eyes were classified into an upper LDO group (29 eyes) and a lower LDO group (65 eyes). We collected ocular surface parameters, including mean non-invasive tear breakup time (NIBUT), Sjögren's International Collaborative Clinical Alliance Ocular Staining Score (SICCA OSS), and Korb scores for the lid wiper. A comparative analysis was performed to evaluate differences in these parameters between the two groups.
resultsSignificant differences were observed in NIBUT and SICCA OSS between the two groups (P
conclusionThe location of obstruction is associated with distinct ocular surface phenotypes. Upper LDO is linked to more severe ocular surface and lid margin damage but relatively preserved tear film stability. Lower LDO is characterized by more profound tear film instability. Therefore, surgical management should be tailored accordingly: procedures for upper LDO should be approached with caution, while prompt intervention is recommended for lower LDO presenting with epiphora.
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