Evidence map›Paper›PMID 41331437›Full record

ArticleBMC microbiology2025

Genetic features of bla

Sajad Aslani, Ali Afgar, Alireza Ekrami, Mohammad Savari, Elham Isaei, Seyed Moein Hosseini, Davood Kalantar-Neyestanaki

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In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sajad AslaniDepartment of Medical Biotechnology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ali AfgarResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Alireza EkramiInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mohammad SavariInfectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Elham IsaeiMedical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Seyed Moein HosseiniStudent Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
Davood Kalantar-NeyestanakiMedical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman, Iran. d.kalantar@kmu.ac.ir.ORCID 0000-0002-8694-2888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe genetic features of harboring Klebsiella pneumoniae isolates from Kerman, Iran, are important to investigate, as they can reveal the genetic diversity, resistance mechanisms, and potential virulence of these clinically significant strains, contributing to better understanding and control of their spread in both local and global contexts.

methodsIn this study, we report the genetic features of 37 NDM-1-harboring K. pneumoniae, including the ability to biofilm formation, resistance genes, virulence factors, toxin-antitoxin systems (TAs), class of integrons, gene mapping of the bla

resultsAll isolates were biofilm producers, and serotype K20 was the most common capsular type. Various virulence factors were detected among the NDM-1-harboring K. pneumoniae, but they were not hypervirulent K. pneumoniae (hv-KP). Class I integrons were identified in all isolates, and 62% (23/37) of the isolates carried at least one gene in the variable region of the class 1 integron. The pemI/pemK, ccdA/ccdB, and hok/sok TAs were found in 100% (37/37) of the isolates. The downstream region sequences of the bla

conclusionOur study revealed genetic diversity, high pathogenicity, and resistance to various antibiotic agents in NDM-1-harboring K. pneumoniae, which can cause significant concern in hospital settings.

Indexed as

beta-LactamasesKlebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsBiofilmsDrug Resistance, Multiple, BacterialGenetic VariationHumansIntegronsIranMicrobial Sensitivity TestsVirulenceVirulence FactorsAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesVirulence Factorsbla NDM−1ERIC-PCRKlebsiella pneumoniaeToxin-antitoxin systemsVirulence genes

Identifiers

PMID41331437
PMCPMC12781302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.