Evidence map›Paper›PMID 41331233›Full record

SynthesisAmerican journal of clinical dermatology2026

Menopause and Common Dermatoses: A Systematic Review.

Katie Roster, Lauren Fleshner, Turkan Banu Karatas, Anna Ecanow, Alyssa Sayegh, Banu Farabi, Shoshana Marmon

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of clinical dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Sex Hormones in Psoriatic Disease: A Systematic Review.American journal of clinical dermatology · 2026
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katie Roster *Department of Dermatology, Georgetown University School of Medicine, Medstar Washington Hospital Center, Washington, D.C., USA.
Lauren Fleshner *New York Medical College, Valhalla, NY, USA.
Turkan Banu Karatas *Emory University School of Medicine, Atlanta, GA, USA.
Anna EcanowNew York Medical College, Valhalla, NY, USA.
Alyssa SayeghNew York Medical College, Valhalla, NY, USA.
Banu FarabiNew York Medical College, Valhalla, NY, USA.
Shoshana MarmonNew York Medical College, Valhalla, NY, USA. Shoshana.Marmon@nychhc.org.ORCID http://orcid.org/0000-0002-8489-961X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMenopause is a universal physiological transition, marked by a decline in estrogen, which has important effects on skin and mucosal health. The impact of menopause and menopausal hormone therapy (MHT) on chronic dermatoses remains incompletely defined.

objectiveThe aim was to investigate the relationship between menopause, MHT, and common dermatological conditions.

methodsPubMed, Embase, and Web of Science were searched from inception to September 2024 in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eligible studies evaluated menopause or MHT in relation to alopecia, psoriasis, acne, rosacea, melasma, and hidradenitis suppurativa (HS). Investigational cohorts largely consisted of menopausal women, although participant characteristics varied. Data on study design, population, hormonal status, and dermatological outcomes were extracted and synthesized.

resultsA total of 40 studies met inclusion criteria. Alopecia, particularly frontal fibrosing alopecia (FFA) and female pattern hair loss (FPHL), showed the strongest postmenopausal associations, with most cases presenting after menopause and earlier or surgical menopause conferring greater risk. Psoriasis frequently persisted or worsened after menopause, though objective assessments are limited. Acne and rosacea generally improved, whereas melasma showed mixed outcomes, including greater extra-facial involvement post menopause. HS responses to menopause were inconsistent. MHT was linked to increased risk of FFA and rosacea, whereas findings for other dermatoses were more variable or absent. Most of the studies involved MHT formulations that are less commonly used in current clinical practice.

conclusionMenopause influences the onset and course of several chronic dermatoses, while data on MHT remain more limited and inconsistent. Dermatologists should consider menopausal status and hormone therapy exposure when evaluating skin disease. Longitudinal, dermatology-focused studies-particularly those integrating diverse populations and updated hormone therapies-are needed to inform individualized care.

Indexed as

Estrogen Replacement TherapyMenopauseSkin DiseasesFemaleHumans

Identifiers

PMID41331233
PMCPMC12860752

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.