Evidence map›Paper›PMID 41331124›Full record

SynthesisCardiovascular and interventional radiology2026

Tunneled Peripherally Inserted Central Catheters and Bloodstream Infection: A Systematic Review and Meta-Analysis.

Dong Jae Shim, Eung Tae Kim, Jae Hwan Lee, Yohan Kwon, Soo Buem Cho, Chang Jin Yoon, Seungjae Lee, John Fritz Angle, Hyungoo Shin

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dong Jae Shim *Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Eung Tae Kim *Department of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri-Si, Gyeonggi-Do, Republic of Korea.
Jae Hwan LeeDepartment of Radiology, Seoul National University Bundang Hospital, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-Si, Gyeonggi-Do, Republic of Korea. lzhwanmd@gmail.com.ORCID http://orcid.org/0000-0001-6513-3224
Yohan KwonDepartment of Radiology, Seoul 88 Clinic, Suwon, Gyeonggi-Do, Republic of Korea.
Soo Buem ChoDepartment of Radiology, College of Medicine, Ewha Womans University Seoul Hospital, Ewha Womans University, Seoul, Republic of Korea.
Chang Jin YoonDepartment of Radiology, Seoul National University Bundang Hospital, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-Si, Gyeonggi-Do, Republic of Korea.
Seungjae LeeDepartment of Applied Statistics, Kyonggi University, Suwon, Republic of Korea.
John Fritz AngleDivision of Vascular and Interventional Radiology, University of Virginia Health System, Charlottesville, VA, USA.
Hyungoo ShinDepartment of Emergency Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to determine whether central line-associated bloodstream infection (CLABSI) rates differ between tunneled and conventionally inserted PICCs (tPICCs and cPICCs). MATERIALS AND

methodsThis systematic review and meta-analysis was prospectively registered in PROSPERO (CRD42024616470) and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Embase, and the Cochrane Library were comprehensively searched from inception to November 27, 2024, to identify randomized controlled trials that compared CLABSI rates between tPICCs and cPICCs. Risk ratios along with the 95% confidence intervals (CI) were calculated for outcomes using a random-effects meta-analysis model following the Hartung-Knapp-Sidik-Jonkman method. Statistical heterogeneity was assessed using the I

resultsA meta-analysis of four relevant studies, comprising 2,659 participants (pooled mean age ± standard deviation, 59.3 ± 15.5 years; 1,481 women) and 177,879 catheter days, revealed overall CLABSI rates of 0.31 per 1,000 catheter-days in the tPICC group and 0.68 per 1,000 catheter-days in the cPICC group. The risk ratio (0.48; 95% CI, 0.28-0.81; p = 0.02) indicated a 52% reduction in the tPICC group compared with the cPICC group, with low heterogeneity (I

conclusionSubcutaneous tunneling for PICC placement is associated with a significant reduction in CLABSI rate among hospitalized adult patients.

Indexed as

Catheterization, PeripheralCatheter-Related InfectionsCentral Venous CathetersHumansBloodstream infectionsCatheterizationPeripheralSubcutaneous tissueVascular access device

Identifiers

PMID41331124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.