Evidence map›Paper›PMID 41330924›Full record

ArticleNature communications2025

Ratiometric detection of perfluoroalkyl carboxylic acids using dual fluorescent nanoparticles and a miniaturised microfluidic platform.

Yijuan Sun, Víctor Pérez-Padilla, Virginia Valderrey, Jérémy Bell, Kornelia Gawlitza, Knut Rurack

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Designed for forever.Nature chemistry · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yijuan Sun *Bundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany.ORCID http://orcid.org/0000-0002-6751-2479
Víctor Pérez-Padilla *Bundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany.ORCID http://orcid.org/0000-0001-6244-7439
Virginia ValderreyBundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany.
Jérémy BellBundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany.ORCID http://orcid.org/0000-0003-1861-1670
Kornelia GawlitzaBundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany.ORCID http://orcid.org/0000-0002-2043-4522
Knut RurackBundesanstalt für Materialforschung und -prüfung (BAM), Berlin, Germany. knut.rurack@bam.de.ORCID http://orcid.org/0000-0002-5589-5548

Funding

China Scholarship Council (CSC) 201908330307CSC | Chinese Government Scholarship 201908330307EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Societal Challenges | H2020 Health (H2020 Societal Challenges - Health, Demographic Change and Well-being) 848098EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 848098
6 · The paper itself

Abstract

The widespread contamination of soil and water with perfluoroalkyl substances (PFAS) has caused considerable societal and scientific concern. Legislative measures and an increased need for remediation require effective on-site analytical methods for PFAS management. Here we report on the development of a green-fluorescent guanidine-BODIPY indicator monomer incorporated into a molecularly imprinted polymer (MIP) for the selective detection of perfluorooctanoic acid (PFOA). Complexation of PFOA by the indicator, which is mediated by concerted protonation-induced ion pairing-assisted hydrogen bonding, significantly enhances fluorescence in polar organic solvents. The MIP forms as a thin layer on silica nanoparticles doped with tris(bipyridine)ruthenium(II) chloride, which provides an orange emission signal as internal reference, resulting in low measurement uncertainties. Using a liquid-liquid extraction protocol, this assay enables the direct detection of PFOA in environmental water samples and achieves a detection limit of 0.11 µM. Integration into an opto-microfluidic system enables a compact and user-friendly system for detecting PFOA in less than 15 minutes.

Identifiers

PMID41330924
PMCPMC12675511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.