Evidence map›Paper›PMID 41330175›Full record

ArticleSeminars in arthritis and rheumatism2025

Magnetic resonance imaging for adult idiopathic inflammatory myopathies: A scoping review of protocols, grading systems and applications.

Jessica A Day, Daniel Brito de Araújo, Mickael Essouma, Edoardo Conticini, Lisa G Rider, Daren Gibson, Adriana Maluf Elias, Claudia Saad Magalhães, Simone Appenzeller, Adam Schiffenbauer and 8 more

Erratum issuedAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Seminars in arthritis and rheumatism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Jessica A DayThe Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; Royal Melbourne Hospital, Melbourne, Victoria, Australia; The University of Melbourne, Melbourne, Victoria, Australia. Electronic address: day.j@wehi.edu.au.
Daniel Brito de AraújoInternal Medicine Department, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, RS, Brazil.
Mickael EssoumaNetwork of Immunity in Infection, Malignancy and Autoimmunity, Universal Scientific Education and Research Network, Yaounde, Cameroon.
Edoardo ConticiniRheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Lisa G RiderEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, United States.
Daren GibsonMedical Imaging, Fiona Stanley Hospital, Murdoch, Australia.
Adriana Maluf EliasPediatric Rheumatology Unit, Children's Institute, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Claudia Saad MagalhãesPediatric Rheumatology Unit, Department of Pathology, Botucatu Medical School, São Paulo State University, Botucatu, São Paulo, Brazil.
Simone AppenzellerDepartment of Orthopedics, Rheumatology and Traumatology, University of Campinas, Campinas, SP, Brazil.
Adam SchiffenbauerEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, United States.
Anneke J van der KoiDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, the Netherlands.
Siamak Moghadam-KiaDivision of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Vitor Tavares PaulaMusculokeletal radiologist. Radiology Department, Children's Institute, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil; Hospital Israelita Albert Einstein, SP, Brazil.
Julio Brandão GuimarãesUniversidade Federal de São Paulo, EPM-UNIFESP, São Paulo, Brazil; Grupo Fleury Medicina e Saúde, São Paulo, Brazil.
Edoardo MarraniRheumatology Unit, ERN-ReCONNET Center, Meyer Children's Hospital IRCCS, Florence, Italy.
Andrea Schwarz DoriaDepartment of Diagnostic & Interventional Radiology, Research Institute, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Samuel Katsuyuki ShinjoDivision of Rheumatology, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
IMACS WBMRI in Myopathies Working Group

Funding

Assessment, Therapy and Prevention Of Autoimmune DiseaseZIAES101081 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI RIDER, LISA · 2009 to 2025
$17.6M
Intramural NIH HHS ZIA ES101081
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) has emerged as a key non-invasive tool for the evaluation of idiopathic inflammatory myopathies (IIM); however, heterogeneity in techniques, protocols, and grading systemics impedes standardization. This scoping review systematically examined the MRI techniques, protocols, and grading systems reported in the adult IIM literature. A systematic search of PubMed, EMBASE, and Cochrane databases was conducted from 2000 to 2024 using keywords related to IIM and MRI. Studies involving adults with IIM who underwent MRI were screened and reviewed for inclusion. Forty-nine studies were included in the analysis, 13 of which evaluated whole-body MRI and 36 evaluated dedicated body-part MRI, collectively reporting data from 2810 IIM patients. A wide range of imaging protocols was observed with variations in scanner type, field strength, sequence combinations, and anatomical coverage. Semi-quantitative visual grading was the most commonly used assessment method (31/49, 63.2 %), with binary scoring in 23/31 and software-assisted or automated techniques in 8/31. Six studies used descriptive analysis alone. Inter-rater agreement was reported in 15 studies, with variable reliability observed for both muscle edema (intraclass correlation coefficient [ICC] range: 0.78-1.00; kappa range: 0.30-1.00) and replacement of skeletal muscle by fat (ICC range: 0.77-0.97; kappa range: 0.54-0.93). Several studies have reported that WB-MRI patterns correlate with clinical measures of disease activity and can discriminate between myopathic diseases and IIM subtypes. In summary, despite the clinical utility of MRI for IIM, significant methodological variability remains. Future research should focus on standardizing protocols and grading systems to enhance the consistency and reliability of MRI assessments for IIM.

Indexed as

Magnetic Resonance ImagingMyositisAdultHumansSeverity of Illness IndexIdiopathic inflammatory myopathiesMagnetic resonance imagingMRIMyositis

Identifiers

PMID41330175
PMCPMC13050306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.