Evidence map›Paper›PMID 41329835›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2026

Descriptive Summary and Experience Introducing the Orthodontic Airway Plate to Treat Upper Airway Obstruction for Infants With Robin Sequence.

Hannah F Case, Marielena Layuno Matos, Kayen Tang, Lindsay Boven, Kara Brodie, Michael Barbour, Lindsey Benedict, Zeenia C Billimoria, Randall Bly, Tracy Brundage and 6 more

Abstract read
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Patient-Specific Computational Fluid Dynamics Modeling of Airway Collapse in Infants With Robin Sequence.International journal for numerical methods in biomedical engineering · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hannah F CaseDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, WA, USA.ORCID 0000-0003-4097-9500
Marielena Layuno MatosCraniofacial Orthodontics, Seattle Children's Hospital, Seattle, WA, USA.ORCID 0009-0009-2786-8444
Kayen TangUniversity of Washington School of Medicine, University of Washington, Seattle, WA, USA.ORCID 0009-0004-5171-7594
Lindsay BovenDivision of Pediatric Otolaryngology, Seattle Children's, Seattle, WA, USA.
Kara BrodieDivision of Pediatric Otolaryngology, Seattle Children's, Seattle, WA, USA.ORCID 0000-0002-2140-0084
Michael BarbourCenter for Respiratory Biology and Therapeutics, Seattle Children's, Seattle, WA, USA.ORCID 0000-0001-5160-0119
Lindsey BenedictCraniofacial Center, Seattle Children's Hospital, Seattle, WA, USA.
Zeenia C BillimoriaDivision of Neonatology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA, USA.ORCID 0000-0002-4843-6271
Randall BlyDivision of Pediatric Otolaryngology, Seattle Children's, Seattle, WA, USA.
Tracy BrundageCraniofacial Center, Seattle Children's Hospital, Seattle, WA, USA.
Maida ChenDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA, USA.ORCID 0000-0002-0470-0245
Jake DahlDepartment of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2728-3576
Seth D FriedmanCenter for Respiratory Biology and Therapeutics, Seattle Children's, Seattle, WA, USA.
Lucy MoremanCraniofacial Center, Seattle Children's Hospital, Seattle, WA, USA.
Barbara ShellerCraniofacial Orthodontics, Seattle Children's Hospital, Seattle, WA, USA.
Kelly EvansCraniofacial Center, Seattle Children's Hospital, Seattle, WA, USA.ORCID 0000-0002-0345-824X

Funding

Clinician-Scientist Research Education and Training in OtolaryngologyR25DC021791 · NIDCD · UNIVERSITY OF WASHINGTON · PI Jay T. Rubinstein, Jennifer S. Stone · 2024 to 2026
$1.6M
NIDCD NIH HHS R25 DC021791
6 · The paper itself

Abstract

Objectives(1) Provide our narrative experience treating patients with Robin Sequence (RS) with our orthodontic airway plate (OAP) protocol and (2) report initial patient outcomes. A secondary objective is to share OAP clinician survey results.Design(1) Narrative experience of a care pathway for neonates with RS and upper airway obstruction (UAO). (2) Retrospective review of initial series of patients with RS treated with this pathway. A clinician survey was also administered.SettingNeonatal intensive care unit and acute care units of a tertiary children's hospital, with continuity outpatient multidisciplinary craniofacial clinic care.Patients and ParticipantsNeonates with RS and severe base of tongue UAO not stabilized with positioning, and without mechanical ventilation, profound dysphagia, or microstomia.InterventionsAdapt an OAP clinical pathwayMain Outcome Measure(s)Lessons learned, clinical course, and respiratory metrics.ResultsIn August 2023, our institution launched an OAP treatment pathway. Lessons learned highlight the importance of multidisciplinary communication, patient selection, and patience. Nine patients completed OAP therapy. oAHI values improved from mean 71/h (range 16-189, SD 55.1) to mean oAHI 7.9/h (range 1.1-12.7, SD 3.8). Pretreatment, 7 patients were on high-flow nasal cannula, one each on low-flow nasal cannula and continuous positive airway pressure. All OAP graduates advanced to room air. Clinician survey results suggested high OAP care preparedness and satisfaction.ConclusionsThe OAP can be introduced in new setting and delivered as a safe and effective nonsurgical intervention for UAO in RS. Interdisciplinary collaboration is key to treatment success. Infants undergoing OAP treatment can safely discharge home and experience sustained respiratory improvements.

Indexed as

Airway ObstructionPierre Robin SyndromeFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesTreatment Outcomeorthodontic airway plateRobin sequenceupper airway obstruction

Identifiers

PMID41329835
PMCPMC13162521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.