ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2026
Predicting Communication-Related Quality of Life in Children With Velopharyngeal Dysfunction.
Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveThe purpose of this study was to determine factors predicting communication-related quality of life in children with cleft palate with or without cleft lip (CP ± L) or congenital velopharyngeal insufficiency (VPI).DesignCross-sectional design.SettingOutpatient pediatric craniofacial anomalies clinic.PatientsTwo-hundred and seventy-one children <18 years of age, diagnosed with CP ± L or congenital VPI.Main Outcome MeasureVelopharyngeal Insufficiency Quality of Life (VELO) scores as well as articulation, speech intelligibility, resonance, and voice outcomes were extracted from the electronic medical record in order to characterize communication-related quality of life. Total VELO score, as well as speech limitations, situational difficulty, emotional impact, perception by others and swallow subscores, were collected. Demographic factors, economic deprivation, medical history, and history of palatoplasty/pharyngoplasty were considered. Linear regression identified predictors of VELO total and subscores.ResultsPoorer speech intelligibility and increased hypernasality significantly predicted lower (worse) total VELO scores (
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