Evidence map›Paper›PMID 41329736›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Systematic analysis of noncanonical ribosomal protein paralogs does not provide evidence for specialized functions in

Katarina Z A Grobicki, Daniel Gebert, Carol Sun, Felipe Karam Teixeira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katarina Z A GrobickiDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0002-1800-2763
Daniel GebertDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Carol SunDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.ORCID 0009-0007-0205-6541
Felipe Karam TeixeiraDepartment of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.ORCID 0000-0001-7651-1657

Funding

Deutsche Forschungsgemeinschaft (DFG) GE3407/1-1European Molecular Biology Organization (EMBO) 5025Human Frontier Science Program (HFSP) CDA-00032/2018UKRI | Medical Research Council (MRC) 2499297Wellcome Trust (WT) 206257/Z/17/Z
6 · The paper itself

Abstract

Ribosomes catalyze all protein synthesis, and mutations altering their levels and function underlie many developmental diseases and cancer. Historically considered to be invariant machines, ribosomes differ in composition between tissues and developmental stages, incorporating a diversity of ribosomal proteins (RPs) encoded by duplicated paralogous genes. Here, we use

Indexed as

Drosophila melanogasterDrosophila ProteinsRibosomal ProteinsAnimalsFemaleGene DuplicationOogenesisRibosomesDrosophila ProteinsRibosomal Proteinsgermlineribosome heterogeneitytranslational control

Identifiers

PMID41329736
PMCPMC12704716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.