Evidence map›Paper›PMID 41329727›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

LUMINIDEPENDENS orchestrates global transcriptional repression in

Clara Bergis-Ser, Qingyi Wang, Xiaoning He, Maherun Nisa, Vickie Kaiser, Christelle Mazubert, Jeannine Drouin-Wahbi, Rim Brik-Chaouche, Layla Chmaiss, Jelle Van Leene and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Clara Bergis-SerUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.ORCID 0000-0002-4003-4761
Qingyi WangUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.ORCID 0009-0009-2171-1622
Xiaoning HeUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.ORCID 0000-0003-2962-8590
Maherun NisaUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.ORCID 0000-0002-6135-4836
Vickie KaiserUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Christelle MazubertUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Jeannine Drouin-WahbiUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Rim Brik-ChaoucheUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Layla ChmaissUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Jelle Van LeeneDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent B-9052, Belgium.ORCID 0000-0002-4932-8192
Geert De JaegerDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent B-9052, Belgium.ORCID 0000-0001-6558-5669
Jose Gutierrez-MarcosSchool of Life Science, University of Warwick, Coventry CV4 7AL, United Kingdom.ORCID 0000-0002-5441-9080
Catherine BergouniouxUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Clara BourbousseSorbonne Université, CNRS, INSERM, Development, Adaptation and Ageing, Paris 75005, France.ORCID 0000-0001-6464-6124
David LatrasseUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Moussa BenhamedUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.
Cécile RaynaudUniversité Paris-Saclay, CNRS, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Univ Evry, Institute of Plant Sciences Paris-Saclay, Orsay 91405, France.ORCID 0000-0002-5231-8120

Funding

Agence Nationale de la Recherche (ANR) 21-CE20-0027Chinese Council Scholarships NAFondation pour la Recherche Médicale (FRM) ECO201806006824Ministère de l'Education Nationale, de l'Enseignement Supérieur et de la Recherche (MENESR) NA
6 · The paper itself

Abstract

Genomic integrity is constantly challenged by transcription/replication conflicts, a major source of replication stress and instability across all life forms. While extensive studies have elucidated mechanisms for resolving transcription/replication conflicts in animals, yeast, and prokaryotes, their counterparts in plants remain largely unexplored. Through a forward genetic screen, we identified LUMINIDEPENDENS (LD), previously known for its role in regulating the flowering repressor

Indexed as

ArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantTranscription, GeneticDNA ReplicationMediator ComplexRNA Polymerase IIArabidopsis ProteinsMediator ComplexRNA Polymerase IIreplication stressRNA polymerasetranscription

Identifiers

PMID41329727
PMCPMC12704789

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.