Reducing use of desflurane in the anaesthetic department: A controlled interrupted time series analysis.

Luise Kazda, Kristen M Pickles, Anthony Hull, Alexandra L Barratt, NSW Health Net Zero Clinical Leads Program

Abstract read

In one paragraph

Article in Anaesthesia and intensive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luise KazdaHealthy Environments and Lives (HEAL) Global Research Centre, Health Research Institute, University of Canberra, Canberra, Australia.ORCID 0000-0003-4105-0402

Kristen M PicklesWiser Healthcare Research Collaboration, Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0002-1621-3217

Anthony HullNSW Health Net Zero Clinical Lead, Bankstown-Lidcombe Hospital, Sydney, Australia.

Alexandra L BarrattWiser Healthcare Research Collaboration, Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

NSW Health Net Zero Clinical Leads Program

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desflurane is a potent and expensive greenhouse gas. Reducing its use is a global priority. This anaesthetist-led quality improvement project involved educational, motivational and system-change initiatives implemented in the anaesthesia department of Bankstown-Lidcombe Hospital (BLH) (September 2021-March 2024), with the aim of reducing desflurane consumption. A quasi-experimental interrupted time series design with control site was employed to estimate changes in usage, greenhouse gas emissions and financial cost of anaesthetic agents per 100 surgeries. Prior to intervention, use of desflurane at BLH was stable. During and after intervention, a significant downward trend in desflurane use was observed, reducing by an average of 0.1 units (1 unit = 1 bottle) per month per 100 surgeries from September 2021 onwards (95% confidence interval (CI) -0.21 to -0.01,

Indexed as

Anesthesia Department, HospitalAnesthetics, InhalationDesfluraneHumansInterrupted Time Series AnalysisQuality ImprovementSevofluraneAnesthetics, InhalationDesfluraneSevofluraneanaesthesiacarboncostDesfluraneenvironmentgreenhouse gasquality improvementsustainability

Identifiers

PMID41329707

DOI10.1177/0310057X251374691

PMCPMC12779768

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.