Evidence map›Paper›PMID 41329687›Full record

ReviewChemical senses2025

Opponent coding mechanisms in Drosophila taste neurons.

Christopher Creighton, Anupama Dahanukar

Abstract readReview
In one paragraph

Review in Chemical senses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher CreightonInterdepartmental Neuroscience Program, University of California, Riverside, CA 92521, United States.ORCID 0000-0002-7742-5168
Anupama DahanukarInterdepartmental Neuroscience Program, University of California, Riverside, CA 92521, United States.ORCID 0000-0003-0534-7700

Funding

Identification of powerful repellents that target mosquito olfaction, gustation and the Na-channelR01DC022286 · NIDCD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Anandasankar Ray · 2025 to 2026
$1.0M
Olfactory and gustatory detection of aversive skin compounds by mosquitoesR56AI180224 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DAHANUKAR, ANUPAMA ARUN, RAY, ANANDASANKAR · 2024 to 2024
$505k
National Institute of Food and Agriculture-U.S. Department of Agriculture 1011543National Science Foundation IOS-2420708NIAID NIH HHS R56 AI180224NIDCD NIH HHS R01 DC022286NIH HHS R01DC22286NIH HHS R56AI180224
6 · The paper itself

Abstract

The ability to discern nutritious food from harmful substances is critical for animal survival, with the gustatory system playing a pivotal role. In insects, including the genetic model Drosophila melanogaster, taste perception involves more than the established valence-based labeled line model, where distinct populations of taste neurons encode appetitive versus aversive stimuli and their activation promotes either attraction or rejection behaviors. A growing body of evidence reveals that sophisticated opponent coding mechanisms operate at multiple levels to modulate responses of taste neurons, enabling dynamic integration between competing taste modalities. These processes significantly expand the informational capacity and behavioral flexibility of the taste system, allowing animals to make appropriate feeding decisions in complex chemical environments where tastants of multiple modalities are simultaneously present.

Indexed as

Drosophila melanogasterNeuronsTasteTaste PerceptionAnimalsbitterDrosophilaopponent codingreceptorssweettaste

Identifiers

PMID41329687
PMCPMC12697163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.