Biophysical and Biochemical Characterization of High Molecular Weight Co-Polymerized Human Hemoglobin and Albumin as a Potential Hemoglobin-Based Oxygen Carrier.
Article in ACS biomaterials science & engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Mohd Asim KhanWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio43210, United States of America.ORCID 0000-0002-4698-2332
Tanmay SalviWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio43210, United States of America.ORCID 0000-0002-2538-3920
Griffin J BeyerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio43210, United States of America.ORCID 0009-0009-6367-3046
Elliot WiddDepartment of Bioengineering, University of California San Diego, San Diego, California92093, United States.
Jacinda MartinezDepartment of Bioengineering, University of California San Diego, San Diego, California92093, United States.
Carlos MunozDepartment of Bioengineering, University of California San Diego, San Diego, California92093, United States.
Pedro CabralesDepartment of Bioengineering, University of California San Diego, San Diego, California92093, United States.ORCID 0000-0002-8794-2839
Andre F PalmerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio43210, United States of America.
Funding
Bioengineering a Dual Function Protein Construct to Detoxify Heme and HemoglobinR01HL159862 · NHLBI · OHIO STATE UNIVERSITY · PI BUEHLER, PAUL WERNER, CABRALES, PEDRO · 2021 to 2024
$2.6M
Bioengineering a novel therapeutic protein complex to minimize the effects of medical device induced hemolysisR01HL162120 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BUEHLER, PAUL WERNER, CABRALES, PEDRO · 2022 to 2025
$2.6M
Engineering a novel biomaterial for oxygen transport applicationsR01HL156526 · NHLBI · OHIO STATE UNIVERSITY · PI BUEHLER, PAUL WERNER, PALMER, ANDRE FRANCIS · 2021 to 2024
$2.5M
Attenuating the Oxidative and Myocardial Side-Effects of Acellular HemoglobinR01HL126945 · NHLBI · OHIO STATE UNIVERSITY · PI CABRALES, PEDRO, PALMER, ANDRE FRANCIS · 2016 to 2019
$1.7M
Training in Bioengineering Research and Technology Development in Cardiovascular in Cardiopulmonary Health and DiseaseT32HL160507 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Karen L Christman, Andrew D. McCulloch · 2022 to 2026
Human hemoglobin (hHb) in the tense (T) quaternary state was copolymerized with human serum albumin (HSA) at various hHb:HSA mass fractions to form polymerized hHb-HSA Poly(hHb:HSA) conjugates as a potential next-generation hemoglobin-based oxygen carrier (HBOC). These conjugates were evaluated for molecular weight (
Indexed as
Blood SubstitutesHemoglobinsOxygenSerum AlbuminSerum Albumin, HumanHumansMolecular WeightOxidation-ReductionPolymerizationBlood SubstitutesHemoglobinsOxygenSerum AlbuminSerum Albumin, Humanco-polymerized hemoglobin and albuminhemoglobin-based oxygen carrieroxygen therapeuticpolymerized human hemoglobinpolymerized human serum albuminred blood cell substitute
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Biophysical and Biochemical Characterization of High Molecular Weight Co-Polymerized Human Hemoglobin and Albumin as a Potential Hemoglobin-Based Oxygen Carrier. · full record | OpenQuestion