Evidence map›Paper›PMID 41328408›Full record

ArticleInfection and drug resistance2025

Clinical and Genomic Characteristics of Carbapenem-Resistant

Fang Qin, Yanjun Liu, Zijuan Jian, Qun Yan, Wenen Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fang Qin *Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Yanjun Liu *Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.ORCID 0000-0001-7673-6370
Zijuan JianDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-2673-7970
Qun YanDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Wenen LiuDepartment of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bloodstream infections (BSIs) caused by carbapenem-resistant Methods: This study collected all eligible older patients (age ≥65 years) with CRKP-BSIs from a national regional medical center in Changsha, China from 2020 to 2023. The identification of CRKP strains was performed using MALDI-TOF mass. The antimicrobial susceptibility testing was evaluated by VITEK 2 Compact system. Clinical data of the patients were collected and a binary logistic regression model was used to analyze the risk factors associated with 30-day mortality. The genomic characteristics of CRKP were characterized by whole-genome sequencing (WGS). Results: A total of 77 older adults with CRKP-BSIs were ultimately included in this study, with an all-cause mortality rate as high as 64.9% (50/77). Mechanical ventilation (OR=8.851; 95% CI 1.503-52.127; Conclusion: CRKP-BSIs in older adults are primarily driven by a limited genetic lineage, ST11, in Changsha, China. Therefore, it is urgently necessary to strengthen the active screening and continuous monitoring of high-risk clone ST11 CRKP among older adults.

Indexed as

bloodstream infectionCRKPgenomic characteristicsmortalityolder adultsrisk factors

Identifiers

PMID41328408
PMCPMC12665234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.