ReviewCurrent research in toxicology2025
Toxicological impacts and mitigation strategies of food contaminants: a global perspective and comprehensive narrative review.
Review in Current research in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Mycotoxin contamination in food and feed: Occurrence, co-occurrence, combined impacts on human and animal health, climate change implications, risk assessment, and mitigation strategies.Mycotoxin research · 2026Review
- One Health approach to radionuclides in milk and meat: Transfer mechanisms, processing effects, regulatory limits, and mitigation strategies.Veterinary world · 2026Review
- A Blockchain-Based Dual-Track Mechanism for Trusted Circulation of Food Safety Detection Data and Batch-Level Risk Control: An Aflatoxin B1 Case Study.Foods (Basel, Switzerland) · 2026Article
- Aflatoxin B1 and food safety: Mechanisms of action associated to Hepatocellular Carcinoma.Archives of microbiology · 2026Review
- Biocontrol of Mycotoxin-Producing Fungi by Lactic Acid Bacteria.Foods (Basel, Switzerland) · 2026Review
- Integrated chemical and radiological risk assessment of livestock products from the Abai region adjacent to the former Semipalatinsk Nuclear Test Site, Kazakhstan.Frontiers in veterinary science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Food contaminants-including chemical, biological, physical, allergenic, and radiological agents-pose major global food safety challenges. This review synthesizes evidence from 2014 to 2025 on Food contaminants sources, cellular and molecular mechanisms, monitoring strategies, and mitigation approaches. Major food contaminants include heavy metals (lead, mercury, cadmium, and arsenic), mycotoxins (aflatoxins, and ochratoxin A), pesticide residues, allergens, microplastics, per- and polyfluoroalkyl substances (PFAS), radioactive isotopes (cesium-137, and iodine-131), and microbial agents such as Bacillus, Salmonella, Listeria, and Escherichia species. At the molecular level, heavy metals trigger oxidative stress, mitochondrial dysfunction, and DNA damage; aflatoxins form DNA adducts, driving carcinogenesis; organophosphate residues inhibit cholinesterase; allergens activate IgE-mediated hypersensitivity; and radiological agents generate reactive oxygen species, causing lipid peroxidation and genomic instability. Regulatory agencies, including WHO, FDA, EFSA, and the European Commission, classify metals as priority hazardous substances and set maximum residue limits (MRLs), tolerable daily intakes (TDIs), and action levels for vulnerable populations, such as children. For example, cadmium in wheat is limited to 100 ppb in the EU, lead in candy to 0.1 ppm, and arsenic in apple juice to 10 ppb. Advanced detection technologies, such as liquid chromatography-mass spectrometry (LC-MS) and inductively coupled plasma mass spectrometry (ICP-MS), enable precise monitoring of contaminants at trace levels. Mitigation strategies emphasize improved agricultural practices, safe processing, allergen control, environmental monitoring, and policy enforcement. Ongoing research on emerging contaminants, particularly PFAS and nanoplastics, is crucial to strengthening food safety systems and protecting public health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.