Evidence map›Paper›PMID 41328344›Full record

ArticleTheranostics2026

Clathrin mediated endocytosis targeting chimera for targeted membrane proteins degradation and enhance CAR-T cell anti-tumor therapy.

Yishuang Li, Zhihong Zhou, Yonghui Lv, Haoneng Hu, Ming Chen, Kunjian Lei, Chuandong Gong, Junzhe Liu, Lufei Yang, Linzhen Huang and 5 more

Abstract read
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yishuang LiDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zhihong ZhouDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Yonghui LvDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Haoneng HuSecond Clinical Medical School, Jiangxi Medical College, Nanchang University, Nanchang, China.
Ming ChenSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, China.
Kunjian LeiDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Chuandong GongDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Junzhe LiuDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Lufei YangDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Linzhen HuangDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Wenji LiuDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Jinying LiDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Minhua YeDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xingen ZhuDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Kai HuangDepartment of Neurosurgery, The 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ClathrinEndocytosisImmunotherapy, AdoptiveMembrane ProteinsNeoplasmsReceptors, Chimeric AntigenT-LymphocytesAnimalsCell Line, TumorCTLA-4 AntigenFemaleHumansMiceProteolysisXenograft Model Antitumor AssaysClathrinCTLA-4 AntigenMembrane ProteinsReceptors, Chimeric AntigenCancer therapyCAR-T cell therapyCleTACEndocytosis degradationTargeted protein degradation

Identifiers

PMID41328344
PMCPMC12665105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.