Evidence map›Paper›PMID 41328315›Full record

SynthesisFrontiers in neurology2025

Clinical efficacy and safety of acupuncture versus Western medicine for insomnia: a systematic review and meta-analysis.

Jun Ma, Meng Peng, Xue-Jiao Xu

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jun MaHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Meng PengHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Xue-Jiao XuHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Insomnia is a common sleep disorder that has a significant impact worldwide and seriously affects the quality of life of patients. Benzodiazepines and non-benzodiazepines are the conventional means of treating insomnia disorder in modern medicine. Acupuncture, as a traditional Chinese medicine therapy, is widely used in the treatment of insomnia disorder. A large number of clinical studies have confirmed the significant efficacy of acupuncture in the treatment of insomnia disorder. The aim of this study is to compare the efficacy and safety of acupuncture and sedative-hypnotic medications in the treatment of insomnia disorder through systematic review and Meta-analysis. To elucidate the efficacy and safety of acupuncture alone in the treatment of insomnia disorder. Methods: A comprehensive computerized literature search was conducted from January 2014 to December 2024 across multiple databases, including VIP Database, Wanfang Data, Cochrane Library, Embase, PubMed, and CNKI to identify studies on acupuncture therapy for patients with insomnia disorder. Two independent researchers performed the data extraction and literature screening processes following standardized protocols. The methodological quality of the included studies was assessed using the Cochrane risk-of-bias tool. Subsequently, a meta-analysis was performed using RevMan 5.4 software, incorporating data from 25 randomized controlled trials (RCTs) that met the predefined inclusion criteria. Results: The meta-analysis results, based on the Pittsburgh Sleep Quality Index (PSQI) scale scores, revealed that acupuncture regimens (MD: -2.52; 95% CI: -3.10 to -1.94; Conclusion: Acupuncture has demonstrated significant efficacy in treating insomnia disorder, with preliminary evidence suggesting a potentially favorable safety profile and minimal adverse effects. However, existing studies exhibit inconsistencies in adverse event reporting and are generally limited by small sample sizes and methodological flaws. Therefore, future research should employ more rigorous study designs, expand participant cohorts, and conduct higher-quality investigations to further validate its efficacy and safety, thereby establishing more robust conclusions. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/, CRD420250653347.

Indexed as

acupunctureinsomniameta-analysisPittsburgh Sleep Quality Indexsystematic review

Identifiers

PMID41328315
PMCPMC12665349

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.