ArticleCurrent research in physiology2025
Serum electrolytes and blood urea nitrogen changes in end-stage renal disease patients undergoing contemporary haemodialysis: A multi-center cross-sectional study.
Article in Current research in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Correction of electrolyte imbalance and adequate haemodialysis (HD) minimizes disease complications and hospitalization. Despite the problem, there is a paucity of data regarding the assessment of serum electrolytes and blood urea nitrogen changes (BUN) in end-stage renal disease patients undergoing contemporary HD in Ethiopia. Objective: The objective of this study was to assess serum electrolytes and BUN changes in patients with End-Stage Renal Disease undergoing contemporary HD in Ethiopia. Methods: A multi-center cross-sectional study was conducted from June 1 to August 10, 2021. The levels of serum electrolytes and BUN before and immediately after HD were measured using an ion-selective electrode and a spectrophotometry analyzer, respectively. Data analysis was performed using SPSS version 26. Descriptive statistics were performed for descriptive variables, and continuous variables were compared as the mean ± SD using a paired Results: The mean ± SD age of the participants was 44.19 ± 15.25 years. The mean ± SD duration of HD was 1.71 ± 1.65 years, and 52 (72.2 %) patients received dialysis twice per week. Compared with immediate postdialysis concentration, a statistically significant decrease was noted for potassium (1.74 ± 1.11 mmol/L, Conclusion: This study found a significant decrease in serum potassium, magnesium, phosphorus, and BUN following dialysis. The urea reduction ratio revealed a minimum adequate HD session among end-stage renal disease patients on maintenance haemodialysis (MHD).
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