Evidence map›Paper›PMID 41328250›Full record

ArticleJournal of advanced veterinary and animal research2025

Development of Montanide-based inactivated vaccine against duck plague virus in Bangladesh.

Layla Yasmin, Md Juwel Hossain, Towhidul Islam, Mohammad Ferdousur Rahman Khan, Marzia Rahman, Tazrin Kamal, K H M Nazmul Hussain Nazir, Md Tanvir Rahman, Rony Ahmed, Mohammad H Rahman and 1 more

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Article in Journal of advanced veterinary and animal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Layla YasminDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Juwel HossainDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Towhidul IslamDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Mohammad Ferdousur Rahman KhanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Marzia RahmanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Tazrin KamalDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
K H M Nazmul Hussain NazirDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Tanvir RahmanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Rony AhmedDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Mohammad H RahmanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Bahanur RahmanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This work aimed to develop Montanide-based inactivated duck plague (DP) vaccines from field isolates in Bangladesh and to evaluate the safety, potency, and efficacy. Materials and Methods: Suspected DP samples such as liver, spleen, trachea, and so on ( Results: The prevalence rate was 65.40% (138/211) of DPV-suspected samples, where Netrokona, Mymensingh, and Kishoreganj were 67.81% (59/87), 64.61% (42/65), and 62.71% (37/59), respectively. The pathogenicity test revealed significant morbidity and mortality in ducklings. Two formulated vaccines comply with the safety criteria in ducklings. In the challenge study, both vaccinated groups (G-1, G-2) achieved 88.89% protection against the virulent DP virus, whereas the control group exhibited 93.33% mortality. The antibody titer measured by ELISA peaked at 21 days and remained till 180 days post-vaccination, which showed a 0.1% ( Conclusion: After 6 months of vaccination, the Montanide ISA 78 VG-based vaccine showed slightly higher immunogenicity than ISA 71, though both were demonstrated to be safe against the DP virus.

Indexed as

DPVefficacyELISAinactivated DP vaccinemontanidepotency

Identifiers

PMID41328250
PMCPMC12665297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.