Evidence map›Paper›PMID 41328237›Full record

ArticleJournal of advanced veterinary and animal research2025

Anti-acne potential of

Siti Hudaidah, Muhammad Kholiqul Amiin, Diki Danar Tri Winanti, Maulid Wahid Yusup, Arief Rahman Rivaie, Syifania Hanifah Samara, Linda Ratna Sari, Gregorius Nugroho Susanto

Abstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siti HudaidahDepartment of Aquaculture, Faculty of Agriculture, Universitas Lampung, Bandar Lampung City, Indonesia.
Muhammad Kholiqul AmiinDepartment of Marine, Faculty of Agriculture, Universitas Lampung, Bandar Lampung City, Indonesia.
Diki Danar Tri WinantiDepartment of Agricultural Product Technology, Faculty of Agriculture, Universitas Lampung, Bandar Lampung City, Indonesia.
Maulid Wahid YusupDepartment of Aquaculture, Faculty of Agriculture, Universitas Lampung, Bandar Lampung City, Indonesia.
Arief Rahman RivaieResearch Center for Fishery, National Research and Innovation Agency (BRIN), Cibinong, Indonesia.
Syifania Hanifah SamaraDepartment of Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Surabaya, Indonesia.
Linda Ratna SariDepartment of Marine, Faculty of Agriculture, Universitas Lampung, Bandar Lampung City, Indonesia.
Gregorius Nugroho SusantoDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Lampung, Bandar Lampung City, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study explores the bioactive compounds in Materials and Methods: 3.3 gm of Results: The GC-MS analysis detected several bioactive compounds in the extract, including fatty acids (e.g., n-hexadecanoic acid and linoleic acid esters), polysaccharides, vitamins, aromatic compounds, and diterpenoids. Fatty acids and vitamin compounds dominated, comprising 72.20% of the extract, with alpha-tocopherol and its derivatives as prominent components. Antimicrobial activity was assessed using the disc-diffusion method. The extract demonstrated notable antibacterial effects, particularly at 10 ppm, achieving inhibition zones of 18.0 ± 2.0 mm against Conclusion: The results indicate that microalgae from the Chlorophyceae class are more effective against Gram-positive than Gram-negative bacteria. These findings emphasize the potential of bioactive compounds as anti-acne agents, suggesting they could serve as substitutes for antibiotics.

Indexed as

anti–acnebioactive compoundGC-MS profilingHaematococcus pluvialisMicroalgaen-hexadecanoic acid

Identifiers

PMID41328237
PMCPMC12665300

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.