ReviewCureus2025
Evolving Horizons in Temporomandibular Joint Total Replacement: A Comprehensive Narrative Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Total temporomandibular joint (TMJ) replacement has become a vital solution for managing end-stage TMJ disorders and significantly enhancing mandibular function and patient quality of life. This narrative review explores the historical developments, clinical objectives, biomaterials, devices, surgical techniques, preoperative preparation, complications, management approaches, and recent innovations in TMJ total joint replacement (TJR). The review draws from a literature search conducted across PubMed, Scopus, Web of Science, and Google Scholar from database inception to August 10, 2025, using terms like "total temporomandibular joint replacement," "TMJ TJR," and "alloplastic TMJ prosthesis," focusing on English-language peer-reviewed articles, reviews, and clinical studies. Current practice leans toward alloplastic reconstruction, utilizing titanium alloys for osseointegration and ultra-high molecular weight polyethylene (UHMWPE) for low-friction surfaces, supported by custom designs via computer-aided design and manufacturing (CAD/CAM). Surgical approaches, including preauricular, retromandibular, and rhytidectomy techniques, have been refined to protect critical structures, such as the facial nerve and internal maxillary artery. Preoperative preparation involves patient education on risks, such as infection and nerve injury; advanced imaging with computed tomography (CT) and 3D reconstructions; and strict aseptic measures. Complications, such as heterotopic bone formation and dislocations, are managed with excision, fat grafting, or surgical redesign, while nerve injuries and synovial issues require targeted interventions. Recent advances have highlighted bioengineered solutions, including bioresorbable composites and nanomaterials, that are promising for merging alloplastic and biological benefits. Currently, these developments, underpinned by ongoing research, position TMJ TJR as a cornerstone of maxillofacial surgery, with the potential to reduce donor morbidity and improve long-term outcomes, although challenges such as infection rates and material hypersensitivity persist, necessitating continued refinement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.