ArticleCureus2025
Penetrating Keratoplasty in a Resource-Constrained Country: Surgical Outcomes and Challenges in the Absence of a Domestic Eye Bank.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCorneal blindness is a significant public health issue worldwide, particularly in resource-constrained countries with limited access to specialized ophthalmic care. Keratoplasty is one of the essential treatment approaches for rehabilitating vision in patients with corneal pathologies.
aimsThe primary aim of the study was to assess the challenges faced during penetrating keratoplasty (PK) and the outcomes of surgeries in a resource-constrained country in the absence of a domestic eye bank. The secondary aim was to assess the outcomes of PK.
methodsThis cross-sectional descriptive study included patients undergoing PK for various corneal pathologies at the Department of Ophthalmology, Medical Teaching Institute, Lady Reading Hospital (MTI-LRH), Peshawar, Pakistan, between January and March 2025.
resultsPK was performed in 42 patients (27 (64.3%) male and 15 (35.7%) female), with a mean age of 33.9 ± 20.9 years. The right eye was involved in 16 (38.1%) patients, while bilateral cases were 13 (31.0%). The leading cause for PK was keratoconus with very low best corrected visual acuity (BCVA) (n = 15, 35.7%), followed by non-traumatic corneal opacity. The waiting period for surgery was >20 months in 31 (73.8%) patients. After PK, the patients who achieved BCVA >6/60 increased from two (4.8%) at one-day follow-up to 29 (69.1%) at six-month follow-up. The major challenge in PK was a lack of surgical tools in 33 (78.6%) patients and a delay in donor tissue availability in 30 (71.4%) patients.
conclusionVisual acuity was significantly improved after PK, particularly at long follow-up periods. The major challenge in PK was the lack of surgical tools and the delay in donor tissue availability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.