ArticleJournal of inflammation research2025
Utility of Magnetic Resonance Imaging in Assessing Disease Activity in Axial Spondyloarthritis Regardless of C-Reactive Protein Status.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Differences in clinical features between axial psoriatic arthritis and axial spondyloarthritis: a systematic review and meta-analysis of observational studies.Frontiers in medicine · 2026Pooled it
- Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype.ACR open rheumatology · 2026Article
- Circulating angiogenic T cells as potential immune-vascular biomarkers associated with disease activity in axial spondyloarthritis.Frontiers in immunology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Magnetic resonance imaging (MRI) and C-reactive protein (CRP) are commonly utilized in the diagnostic and disease activity assessment of axial spondyloarthritis (axSpA). The aim of this analysis is to determine the clinical utility of MRI and CRP in assessing disease activity, particularly in patients with normal CRP levels. Methods: A retrospective evaluation was conducted on patients diagnosed with axSpA who received care at the First Affiliated Hospital of Fujian Medical University between 2022 and 2024. Comparisons were made between patients diagnosed with ankylosing spondylitis (AS) and those with non-radiographic axial spondyloarthritis (nr-axSpA) regarding clinical features, disease activity, and MRI-detected lesions. Results: A total of 719 patients diagnosed with axSpA were included. Of the 638 patients who underwent both MRI and CRP testing, 391 had normal CRP levels, and 247 had elevated CRP levels. Among patients with normal CRP levels, the frequency of active and structural lesions identified on MRI was significantly lower compared to those with elevated CRP levels ( Conclusion: In patients with normal CRP levels, MRI remains a valuable tool for evaluating disease activity in axSpA. The imaging findings indirectly indicate that erosive changes may represent an early stage in the progression from bone marrow edema to structural damage. Nr-axSpA may reflect an earlier disease stage, whereas AS represents a later stage within the axSpA spectrum.
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