ArticleInfection & chemotherapy2025
Low Blood Culture Contamination Rates Sustained in Children during the COVID-19 Pandemic.
Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe coronavirus disease 2019 (COVID-19) pandemic has led to many changes in medical practice. For example, some adult studies have reported that the strict implementation of universal precautions increased blood culture contamination rates. However, little evidence exists in children, and its relevance to pediatrics remains unclear. MATERIALS AND
methodsThis retrospective observational study was conducted at a tertiary children's hospital in Japan where the emergency department (ED) physicians receive active monthly feedback for changes in blood culture contamination rates. The data were extracted from medical records of children under 18 years old. The number of patients who visited the ED, number of blood culture bottles drawn, results of positive blood cultures, and sources of infection were compared between the pre-COVID-19 (1/2017-12/2019) and COVID-19 (1/2020-12/2022) periods.
resultsDuring each period, 83,224 and 57,742 patients visited the ED, and 12,571 and 9,409 blood cultures were obtained, respectively. The contamination rates were unchanged, with average rates of 1.0% in both periods (
conclusionActive feedback is likely to maintain low contamination rates during the pandemic. The decrease in occult bacteremia suggests that enhanced infection control measures influenced pediatric infectious disease patterns.
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