Evidence map›Paper›PMID 41327892›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2026

Mitochondria-Targeted Nanomotor: H

Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M Rosenholm, Zhongwei Zhao and 2 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Mitochondria-Targeted Nanomotor: HAdvanced materials (Deerfield Beach, Fla.) · 2026
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Chengcheng LiZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.ORCID 0009-0006-9900-8804
Xiaodong MaJoint Centre of Translational Medicine, Wenzhou Key Laboratory of Interdiscipline and Translational Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Shiji FangZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.
Biao ChenZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.
Xinru WangJoint Centre of Translational Medicine, Wenzhou Key Laboratory of Interdiscipline and Translational Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Lingyun HeJoint Centre of Translational Medicine, Wenzhou Key Laboratory of Interdiscipline and Translational Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Xin YangJoint Centre of Translational Medicine, Wenzhou Key Laboratory of Interdiscipline and Translational Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Yuanqiang LiPharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, 20500, Finland.
Jessica M RosenholmPharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku, 20500, Finland.
Zhongwei ZhaoZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.
Jiansong JiZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.
Hongbo ZhangZhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, 323000, China.ORCID 0000-0002-1071-4416

Funding

Chengcheng Li CSC202207040015InFLAMES Flagship 337531Research Council of Finland; Natural Science Foundation of Zhejiang Province LLSSZ25H180001Research Project 347897Solution for Health Profile 336355Zhejiang Provincial Natural Science Foundation of China LBD24H180001
6 · The paper itself

Abstract

Despite advances in combination therapies for cancer treatment, most strategies rely on modular-additive designs that lack dynamic molecular cues to achieve intrinsic synergy. Herein, a mitochondrial-targeted nanoplatform is introduced that orchestrates photodynamic therapy (PDT), mild photothermal therapy (mPTT), and enzyme dynamic therapy (EDT) into a self-amplifying cascade network through gasotransmitter (H

Indexed as

Carcinoma, HepatocellularHydrogen SulfideLiver NeoplasmsMitochondriaNanoparticlesAnimalsCell Line, TumorGoldHSP70 Heat-Shock ProteinsHumansMicePhotochemotherapyPhotosensitizing AgentsSilicon DioxideGoldHSP70 Heat-Shock ProteinsHydrogen SulfidePhotosensitizing AgentsSilicon Dioxidecascade therapyenzyme dynamic therapymitochondria‐targetingphotodynamic therapyphotothermal therapy

Identifiers

PMID41327892
PMCPMC12879285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.