Evidence map›Paper›PMID 41327868›Full record

ArticleJournal of medicinal chemistry2025

H

Eron Saxon, Dana Stambekova, Thilini Nimasha Fernando Ponnamperumage, Joseph R Clark, Xiaohua Peng

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eron SaxonDepartment of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, 2000 E. Kenwood Boulevard, Milwaukee, Wisconsin 53211, United States.
Dana StambekovaDepartment of Chemistry, Marquette University, 1414 W Clybourn St, Milwaukee 53233, Wisconsin, United States.
Thilini Nimasha Fernando PonnamperumageDepartment of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, 2000 E. Kenwood Boulevard, Milwaukee, Wisconsin 53211, United States.
Joseph R ClarkDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.
Xiaohua PengDepartment of Chemistry and Biochemistry and the Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, 2000 E. Kenwood Boulevard, Milwaukee, Wisconsin 53211, United States.ORCID 0000-0001-5627-0606

Funding

Molecular Rotational Resonance Spectroscopy Instrumentation for the Quantification and Characterization of EnantioisotopomersR35GM147441 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Joseph Clark · 2022 to 2026
$2.1M
Novel DNA cross-linking agents and combination strategies for tumor-specific activationR15CA277656 · NCI · UNIVERSITY OF WISCONSIN MILWAUKEE · PI PENG, XIAOHUA · 2023 to 2023
$462k
NCI NIH HHS R15 CA277656NIGMS NIH HHS R35 GM147441
6 · The paper itself

Abstract

Boron-based reactive oxygen species (ROS)-activated prodrugs offer a promising strategy for enhancing cancer selectivity, yet their

Indexed as

Antineoplastic AgentsHydrogen PeroxideNitrogen Mustard CompoundsProdrugsAnimalsCell Line, TumorCell ProliferationDeuteriumFemaleHumansMiceMice, NudeReactive Oxygen SpeciesXenograft Model Antitumor AssaysAntineoplastic AgentsDeuteriumHydrogen PeroxideNitrogen Mustard CompoundsProdrugsReactive Oxygen Species

Identifiers

PMID41327868
PMCPMC12703749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.