Evidence map›Paper›PMID 41327501›Full record

ArticleDiagnostic and prognostic research2025

Why we do need explainable AI for healthcare.

Giovanni Cinà, Tabea E Röber, Rob Goedhart, Ş İlker Birbil

Abstract readLetter
In one paragraph

Article in Diagnostic and prognostic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovanni CinàDepartment of Medical Informatics, Amsterdam University Medical Center, Amsterdam, The Netherlands. g.cina@amsterdamumc.nl.
Tabea E RöberDepartment of Business Analytics, Amsterdam Business School, University of Amsterdam, Amsterdam, The Netherlands.
Rob GoedhartDepartment of Business Analytics, Amsterdam Business School, University of Amsterdam, Amsterdam, The Netherlands.
Ş İlker BirbilDepartment of Business Analytics, Amsterdam Business School, University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent uptake in certified Artificial Intelligence (AI) tools for healthcare applications has renewed the debate around their adoption. Explainable AI, the sub-discipline promising to render AI devices more transparent and trustworthy, has also come under scrutiny as part of this discussion. Some experts in the medical AI space debate the reliability of Explainable AI techniques, expressing concerns on their use and inclusion in guidelines and standards. Revisiting such criticisms, this article offers a balanced perspective on the utility of Explainable AI, focusing on the specificity of clinical applications of AI and placing them in the context of healthcare interventions. Against its detractors and despite valid concerns, we argue that the Explainable AI research program is still central to human-machine interaction and ultimately a useful tool against loss of control, a danger that cannot be prevented by rigorous clinical validation alone.

Indexed as

Clinical applicationsExplainable AIMedical AI

Identifiers

PMID41327501
PMCPMC12670843

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.