Evidence map›Paper›PMID 41327429›Full record

ArticleArchives of public health = Archives belges de sante publique2025

Mapping the burden of COVID-19 infections and estimating the contribution of socioeconomic factors: a cross-sectional study.

Karla Margarita Flores-Sacoto, Gregory Guernec, Galo Antonio Sanchez-Del-Hierro, Felipe Gonzalo Moreno-Piedrahita Hernández

Abstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karla Margarita Flores-SacotoFacultad de Medicina, Pontificia Universidad Católica del Ecuador(PUCE), Quito, Ecuador. kmflores@puce.edu.ec.ORCID http://orcid.org/0000-0002-3377-8770
Gregory GuernecUMR-1295-CERPOP, Université Paul Sabatier, Toulouse, France.
Galo Antonio Sanchez-Del-HierroFacultad de Medicina, Pontificia Universidad Católica del Ecuador(PUCE), Quito, Ecuador.ORCID http://orcid.org/0000-0002-4358-3563
Felipe Gonzalo Moreno-Piedrahita HernándezFacultad de Medicina, Pontificia Universidad Católica del Ecuador(PUCE), Quito, Ecuador.ORCID http://orcid.org/0000-0003-0875-7350

Funding

Training Program in Research Ethics in the AmericasR25TW001605 · FIC · YESHIVA UNIVERSITY · PI LUNA, FLORENCIA · 2000 to 2025
$6.7M
FIC NIH HHS R25 TW001605
6 · The paper itself

Abstract

introductionEcuador was among the countries most severely affected by COVID-19, a consequence of its distinct geographical and socioeconomic vulnerabilities. This study seeks to assess the pandemic’s burden in Ecuador during 2020 by quantifying Disability-Adjusted Life Years (DALYs). Furthermore, it investigates the spatial relationship between Years of Life Lost (YLL) and cantonal-level sociodemographic factors, aiming to identify regional disparities and underlying social determinants that contributed to the observed inequities in health outcomes.

methodsThis study conducts a subnational analysis of Ecuador’s COVID-19 burden, examining epidemiological data from February to December 2020 across all 24 provinces and 221 cantons. We utilized morbidity and mortality statistics from the Ministry of Public Health (MoH) alongside national census data to assess disease impact through spatial and demographic disparities. Laboratory-confirmed cases were categorized as deaths or recoveries. DALYs were calculated by gender and age group using the DALY package in R. Spatial autocorrelation analyses were conducted to find associations with locational factors.

resultsA total of 125,383 DALYs were recorded for COVID-19 during the study period. Males experienced higher DALYs (Median = 56,859) than females (Median = 28,344; Mann–Whitney U = 24,427,451, p < 0.0001, Hedges’ g = 0.52). The disease burden was particularly high in individuals aged 60 and older. YLL had a geographic pattern, with higher rates in northern and western Ecuador (global Moran’s I = 3.22, p = 0.0006), and was associated with factors such as literacy, ethnicity, and sanitation.

conclusionsCOVID-19 imposed a substantial burden of disease in Ecuador in 2020, with nearly all DALYs attributable to premature mortality. Geographic and sociodemographic disparities revealed clusters of excess YLL in cantons with limited healthcare access and structural vulnerabilities. These findings underscore the need for equity-oriented policies and geographically targeted interventions to strengthen health system resilience and reduce future pandemic impacts.

Indexed as

COVID-19Disability-Adjusted Life YearsEcuadorMorbidityMortalitySpatial analysisYears of Life LostYears of Life Lost due to Disability

Identifiers

PMID41327429
PMCPMC12683874

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.