ArticleJournal of orthopaedic surgery and research2025
Soft-tissue quadriceps tendon autograft during primary anterior cruciate ligament reconstruction in Skeletally-immature patients vs. Hamstrings: A protocol for a multi-centre randomized controlled trial.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03896464 (Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings (SQuASH): A Multi-Centre Randomized Controlled Trial
Who cites it
1 citing paper in PubMed.
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundACL tears in skeletally-immature patients are often treated surgically using soft-tissue autografts to offset increased risks of cartilage, meniscus and physeal injuries. Despite technological innovation, there remains a high failure rate among active young patients. We present a randomized controlled trial (RCT) to evaluate the soft-tissue quadriceps autograft compared to the standard hamstring autograft to treat primary ACL tears in the pediatric population.
methodsThis international RCT will evaluate 352 skeletally-immature patients between the ages of 10-18 years undergoing primary ACL reconstruction to compare the effect of hamstring versus soft-tissue quadriceps autografts on ACL failure rate as a primary outcome, and return to sport, knee function, knee pain, health-related quality of life and health utility, range of motion and stability, and other adverse events at 24 months as secondary outcomes. Follow-up will occur at 6 weeks and 6, 12, 18, and 24 months postoperatively. DISCUSSION: This trial will inform the optimal primary surgical management for ACL injuries as it pertains to all soft-tissue graft selection, to not only reduce the relatively high failure rates, but also improve the function and return-to-sports in this young, active population.
trial registrationThis trial was registered on ClinicalTrials.gov (NCT03896464) on March 27th, 2019.
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