Observational studyBMC ophthalmology2025
Role of AS-OCT in assessment of healing of thin or perforated cornea treated by amniotic membrane graft and PRP clot.
Observational study in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06422897 (Role of Anterior Segment Optical Coherence Tomography in Assessment of Healing of Thin or Perforated Cornea Treated by Amniotic Membrane Graft and Platelet Rich Plasma Clot), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Anterior Segment Optical Coherence Tomography in Assessment of Healing of Thin or Perforated Cornea Treated by Amniotic Membrane Graft and Platelet Rich Plasma Clot
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of the study is to evaluate the role of anterior segment optical coherence tomography in the assessment of the healing of corneal perforation after surgical treatment by amniotic membrane graft and platelet-rich plasma clot.
methodsProspective, consecutive clinical series of cases. 13 eyes of 13 patients with small corneal perforation or thinning were included in the study. The patients were surgically treated with an amniotic membrane graft (AMG) and a platelet-rich plasma (PRP) clot, and the anterior chamber was reformed using air. Anterior segment optical coherence tomography (AS-OCT) was performed 1 week and 1 month after the surgery to confirm corneal healing and to assess the anterior chamber.
resultsAll cases demonstrated the formation of the anterior chamber and adequate intraocular pressure digitally during the follow-up period, and all cases showed complete healing of the corneal perforation by AS-OCT within the 4-week follow-up period.
conclusionAS-OCT is an essential tool to confirm healing of the corneal perforation surgically treated by amniotic membrane graft and platelet-rich plasma clot.
trial registrationThe study was registered in ClinicalTrials.gov on May 20, 2024, with NCT06422897. The study was approved by the Ethics Committee, Faculty of Medicine, Minia University, El-Minya, Egypt (No. 1133/04/2024). This study adhered to the principles outlined in the Declaration of Helsinki.
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