Observational studyBMC ophthalmology2025
Corneal optical densitometry and anterior segment parameters in healthy upper Egyptian population: a prospective observational cross-sectional study.
Observational study in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundto evaluate corneal optical densitometry (COD) and its associations with age, refractive error, central corneal thickness (CCT), anterior chamber depth (ACD), and corneal curvature in healthy Upper Egyptian subjects.
methodsThis prospective cross-sectional study included 379 eyes of 379 healthy subjects aged 16 years or older. All participants underwent a comprehensive ophthalmologic evaluation. Corneal optical densitometry was assessed using the Oculus Pentacam, which measures COD in grayscale units (GSU) across four annular zones and three lamellar layers. Cases with a history of corneal or intraocular surgery, habitual contact lens use, or systemic diseases were excluded.
resultsThe mean COD over the entire cornea (0–12 mm) was 16.1 ± 2.6 GSU. A strong positive correlation was found between age and COD across all zones and layers (p < 0.001). Negative correlations were observed between COD and mean refractive spherical equivalent (MRSE) in the 10–12 mm zone (p < 0.001) and between COD and CCT in the 0–2 mm zone (p = 0.004). Anterior chamber depth (ACD) was negatively correlated with COD in multiple zones (p < 0.05). Positive correlations were identified between COD and keratometry readings (Km and Kmax) across all zones and layers (p < 0.001).
conclusionThis study highlights the associations between corneal optical densitometry and basic population characteristics in healthy Upper Egyptian subjects. This enhances understanding of factors influencing corneal transparency and underscores the importance of considering these variables in clinical and research settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.