ArticleBMC infectious diseases2025
Bacterial-associated bloodstream infections among hospitalized patients in Lagos, Nigeria.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacterial-associated bloodstream infections (BSIs) pose a significant health challenge, particularly in low- and middle-income countries where diagnostic delays and antimicrobial resistance exacerbate outcomes. This study investigated the prevalence, clinical correlates, bacterial aetiology, and resistance profiles of BSIs among hospitalised febrile patients in Lagos, Nigeria.
methodsA total of 2,940 blood samples were collected from febrile inpatients across five healthcare centres between 2018 and 2023. Standard microbiological techniques and mass spectrometry were employed for bacterial identification. Antimicrobial susceptibility testing was performed following CLSI guidelines. Statistical analyses included chi-square tests, regression modelling, and correlation analysis.
resultsOf the 2,940 samples, 307 (10.44%) were culture-positive, with gram-negative bacteria accounting for 91.8% of isolates. Proteus spp., Escherichia coli, and Klebsiella spp. were the most prevalent pathogens. Septicaemia, bradycardia, and extreme age groups (0-10, ≥ 41 years) were significantly associated with BSIs (p < 0.0001). Multidrug resistance was highest in P. vulgaris (32.7%) and E. coli (27.9%). A strong correlation (R = 0.76) was observed between clinical diagnosis and culture positivity.
conclusionThe findings reveal a high burden of gram-negative bloodstream infections predominantly caused by Proteus spp., E. coli, and Klebsiella spp., with significant multidrug resistance, particularly in P. vulgaris and E. coli, and strong associations with septicaemia, bradycardia, extreme age groups, and clinical diagnoses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.