Evidence map›Paper›PMID 41326865›Full record

ArticleNeurosurgical review2025

Factors influencing immediate post-angiographic occlusion outcomes in intracranial aneurysms treated with the woven endobridge device: a multi-center analysis and predictive model from the WorldWideWEB consortium.

Muhammed Amir Essibayi, Mohamed Sobhi Jabal, Hasan Jamil, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Mahmoud Dibas, Nicole M Cancelliere, Jose Danilo Bengzon Diestro, Oktay Algin and 76 more

Abstract readMulticenter Study
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

86 authors.

Muhammed Amir EssibayiDepartments of Neurological Surgery, Radiology, and Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Mohamed Sobhi JabalDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
Hasan JamilDepartments of Neurological Surgery, Radiology, and Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Hamza Adel SalimDepartment of Radiology, Division of Neuroradiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Basel MusmarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Nimer AdeebDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Mahmoud DibasDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Nicole M CancelliereNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Jose Danilo Bengzon DiestroNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Oktay AlginDepartment of Radiology, Medical Faculty of Ankara University, Ankara, Turkey.
Sherief GhozyDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
Sovann V LayDepartment of Neuroradiology, Centre Hospitalier de Toulouse, Toulouse, France.
Adrien GuenegoDepartment of Neuroradiology, Hôpital Universitaire Erasme, Brussels, Belgium.
Leonardo RenieriDepartment of Neuroradiology, Ospedale Careggi Di Firenze, Florence, Italy.
Joseph CarnevaleDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, NY, USA.
Guillaume SaliouDepartment of Neuroradiology, Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland.
Panagiotis MastorakosDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Kareem El NaamaniDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Arbaz A MominDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Eimad ShotarDepartment of Neuroradiology, Hôpital Pitié-Salpêtrière, Paris, France.
Markus MöhlenbruchDepartment of Neuroradiology, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Michael KralDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.
Charlotte ChungDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Mohamed M SalemDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Ivan LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Paul M ForemanDepartment of Neurosurgery, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
Hamza ShaikhDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Vedran ŽupančićDepartment of Neuroradiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
Muhammad U HafeezDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Joshua CatapanoDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA.
Muhammad WaqasDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Muhammed Said BeslerDepartment of Radiology, Kahramanmaraş Necip Fazıl City Hospital, Kahramanmaraş, Turkey.
Yasin Celal GunesDepartment of Radiology, Kırıkkale Yuksek Ihtisas Hospital, Kırıkkale, Turkey.
James D RabinovNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Julian MaingardDepartment of Neuroradiology, Austin Health, Victoria, Australia.
Clemens M SchirmerDepartment of Neurosurgery and Radiology, Geisinger Hospital, Danville, PA, USA.
Mariangela PianoDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milan, Italy.
Anna L KühnDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, MA, USA.
Caterina MichelozziDepartment of Neuroradiology, Ospedale San Raffaele, Milan, Italy.
Robert M StarkeDepartment of Neurosurgery, University of Miami, Miami, FL, USA.
Ameer HassanDepartment of Neuroradiology, Valley Baptist Neuroscience Institute, Harlingen, TX, USA.
Mark OgilvieDeparments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Anh NguyenDepartment of Neuroradiology, University Hospital of Basel, Basel, Switzerland.
Jesse JonesDeparments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Waleed BrinjikjiDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
Marie T NawkaDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marios PsychogiosDepartment of Neuroradiology, University Hospital of Basel, Basel, Switzerland.
Christian UlfertDepartment of Neuroradiology, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Bryan PukenasDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Jan-Karl BurkhardtDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Thien HuynhDepartments of Radiology and Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Juan Carlos Martinez-GutierrezDepartment of Neuroradiology, University of Texas Health Science Center at Houston, Houston, USA.
Sunil A ShethDepartment of Neuroradiology, University of Texas Health Science Center at Houston, Houston, USA.
Diana SlawskiDepartment of Radiology, Division of Neuroimaging and Neurointervention, Stanford University School of Medicine, Stanford, CA, United States.
Rabih TawkDepartments of Radiology and Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Benjamin PulliDepartment of Radiology, Division of Neuroimaging and Neurointervention, Stanford University School of Medicine, Stanford, CA, United States.
Boris LubiczDepartment of Neuroradiology, Hôpital Universitaire Erasme, Brussels, Belgium.
Pietro PanniDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milan, Italy.
Ajit S PuriDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, MA, USA.
Guglielmo PeroDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milan, Italy.
Eytan RazDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Christoph J GriessenauerDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.
Hamed AsadiDepartment of Neuroradiology, Austin Health, Victoria, Australia.
Adnan SiddiquiDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Elad I LevyDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Deepak KhatriDepartments of Neurological Surgery, Radiology, and Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Neil HaranhalliDepartments of Neurological Surgery, Radiology, and Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Andrew F DucruetDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA.
Felipe C AlbuquerqueDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA.
Robert W RegenhardtNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Christopher J StapletonNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Peter KanDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Vladimir KalousekDepartment of Neuroradiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
Pedro LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Srikanth BodduDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, NY, USA.
Jared KnopmanDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, NY, USA.
Stavropoula I TjoumakarisDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Hugo H Cuellar-SaenzDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Pascal M JabbourDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Frédéric ClarençonDepartment of Neuroradiology, Hôpital Pitié-Salpêtrière, Paris, France.
Nicola LimbucciDepartment of Neurosurgery and Neuroradiology, New York Presbyterian Hospital and Weill Cornell School of Medicine, New York, NY, USA.
Vitor Mendes PereiraNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Aman B PatelNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
David J AltschulDepartments of Neurological Surgery, Radiology, and Montefiore-Einstein Cerebrovascular Research Lab, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA. daltschu@montefiore.org.
Adam A DmytriwNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
WorldWideWEB Consortium Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Woven EndoBridge (WEB) device treats wide-necked bifurcation aneurysms, but occlusion rates vary. This study aims to identify factors associated with immediate WEB device occlusion. Data from patients treated with WEB devices across 36 sites were analyzed. Machine learning algorithms and ordinal regression models were developed to predict immediate incomplete occlusion for ruptured and unruptured aneurysms. The study included 1565 patients, with 436 ruptured and 1129 unruptured aneurysms. Immediate complete occlusion was achieved in 38.3% of ruptured and 32.8% of unruptured aneurysms. For ruptured aneurysms, the CatBoost classifier achieved an AUROC of 0.69. Key predictors of incomplete occlusion included pretreatment mRS, aneurysm diameter, and MCA location. Ordinal regression revealed that smoking history (OR: 1.95, p < 0.001), neck diameter (Odds Ratio [OR]: 1.50, p < 0.001), and presence of a branch from the aneurysm (OR: 2.06, p = 0.016) were associated with incomplete, while bifurcation aneurysms (OR: 0.55, p = 0.017) were associated with complete immediate occlusion. For unruptured aneurysms, the CatBoost classifier achieved an AUROC of 0.68. Significant predictors of immediate incomplete occlusion included aneurysm neck width, MCA location, and presence of daughter sac. Ordinal regression revealed that smoking history (OR: 1.29, p = 0.032), neck diameter (OR: 1.24, p < 0.001), and presence of a daughter sac (OR: 1.53, p = 0.005) were associated with incomplete, while bifurcation aneurysms (OR: 0.71, p = 0.02) and posterior circulation location (OR: 0.68, p = 0.01) were associated with complete immediate occlusion. Careful evaluation of patient demographics and specific aneurysm characteristics may help improve the outcomes of intracranial aneurysms treated with WEB device.

Indexed as

Aneurysm, RupturedEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAdultAgedCerebral AngiographyFemaleHumansMaleMiddle AgedTreatment OutcomeAneurysmsBrainImmediate occlusionWoven EndoBridge

Identifiers

PMID41326865
PMCPMC12669363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.