Evidence map›Paper›PMID 41326816›Full record

Trial reportJournal of assisted reproduction and genetics2026

Feasibility and effectiveness of a health educational intervention to improve navigation of health insurance benefits for in vitro fertilization: a randomized controlled trial.

Olumayowa Dayo, Bonnie N Kaiser, Ricardo E Flores Ortega, Victoria Turcotte, Breanna Reyes, Natasha Bisarya, Brian Kwan, Gregory A Aarons, Sara B McMenamin, H Irene Su and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of assisted reproduction and genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olumayowa DayoDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Bonnie N KaiserAnthropology Department and Global Health Program, University of California San Diego, La Jolla, CA, USA.
Ricardo E Flores OrtegaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Victoria TurcotteDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Breanna ReyesDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Natasha BisaryaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Brian KwanDepartment of Health Science, California State University Long Beach, Long Beach, CA, USA.
Gregory A AaronsDepartment of Psychiatry and ACTRI Dissemination and Implementation Science Center, University of California San Diego, La Jolla, CA, USA.
Sara B McMenaminHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.
H Irene SuDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Sally A D RomeroDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA. saromero@health.ucsd.edu.ORCID http://orcid.org/0000-0001-6028-4111

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
TRAINING IN REPRODUCTIVE SCIENCEST32HD007203 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAMELA L MELLON · 1988 to 2026
$4.8M
Foundation for the National Institutes of Health UL1TR001442NCATS NIH HHS UL1 TR001442NICHD NIH HHS T32 HD007203
6 · The paper itself

Abstract

purposeTo determine the effectiveness of an educational intervention in improving health insurance literacy and utilization of in vitro fertilization insurance benefits.

methodsRandomized controlled trial, with 217 participants randomized in a 2:1 fashion to receive either an educational intervention or university-provided information sheet. Participants were 18 to 50 years, intending to conceive within a year, eligible for employee-offered health insurance coverage. The primary outcome was health insurance literacy. Secondary outcomes included comparing health insurance plans, plan selection, in vitro fertilization service utilization, benefit utilization, out-of-pocket costs, and acceptability, appropriateness, and feasibility of the intervention materials. Semi-structured interviews evaluated participant experiences with intervention materials, plan selection, benefit utilization, in vitro fertilization services, and out-of-pocket costs.

resultsBoth groups reported low confidence using their health insurance (intervention: 1.00 [SD = 0.90], usual care: 0.74 [SD = 0.76], β = 0.26, 95% CI - 0.09, 0.62) and moderately high confidence being proactive when using their health insurance (intervention: 2.26 [SD = 0.86], usual care: 2.47 [SD = 0.58], β =  - 0.20, 95% CI - 0.52, 0.11). Utilization of in vitro fertilization services was similar between groups (intervention: 40% [10/25], usual care: 45% [9/20]; p = 0.35). Use of insurance for these services did not differ between groups (intervention: 36% [9/25], usual care: 40% [8/20]; p = 0.78), and both groups experienced moderate out-of-pocket costs. Qualitative data revealed challenges in benefit utilization in both groups.

conclusionsDespite the educational intervention not improving health insurance literacy or in vitro fertilization benefit utilization, our findings suggest that being able to navigate health insurance benefits is essential for effective utilization of in vitro fertilization services. TRIAL REGISTRATION NUMBER: NTC05663645.

Indexed as

Fertilization in VitroHealth EducationHealth LiteracyInsurance BenefitsInsurance, HealthAdolescentAdultFemaleHumansInsurance CoverageMiddle AgedYoung AdultHealth EducationHealth insurance benefitHealth insurance literacyHealth services accessibilityIn vitro fertilization

Identifiers

PMID41326816
PMCPMC12901767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.