Evidence map›Paper›PMID 41326731›Full record

Observational studySurgical endoscopy2026

Sensory changes in the chin and lower lip after transoral endoscopic thyroidectomy.

Ken Woo, Dong Kun Lee, Phil Sang Chung, Seung Hoon Woo

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ken Woo *Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA, USA.
Dong Kun Lee *Department of Otolaryngology - Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
Phil Sang ChungDepartment of Otolaryngology - Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Korea.
Seung Hoon WooDepartment of Otolaryngology - Head and Neck Surgery, Dankook University College of Medicine, Cheonan, Korea. lesaby@hanmail.net.

Funding

Ministry of Education (MOE) NRF-2020R1A6A1A03043283Ministry of Education (MOE) RS-2020-KD000027Ministry of Education (MOE) RS-2023-00247651Ministry of Science and ICT, the Ministry of Trade, Industry, and Energy (MOTIE, Korea), the Ministry of Health & Welfare, and the Ministry of Food and Drug Safety 20021987Ministry of Science and ICT, the Ministry of Trade, Industry, and Energy (MOTIE, Korea), the Ministry of Health & Welfare, and the Ministry of Food and Drug Safety RS-2020-KD000027SNUH Lee Kun-hee Child Cancer & Rare Disease Project 23C-02300100
6 · The paper itself

Abstract

backgroundMinimally invasive thyroid surgery offers cosmetic benefits over traditional approaches, but mental nerve injury risk affecting the chin and lower lip persists. Transoral endoscopic thyroidectomy within a defined safety zone is a scarless alternative that may cause transient sensory changes.

methodsIn this prospective observational study, 77 patients with benign thyroid conditions were enrolled; after exclusions, 37 underwent transoral endoscopic thyroidectomy and 40 underwent conventional transcutaneous thyroidectomy. Baseline chin and lower lip sensation was quantified preoperatively and postoperatively at 1 week, 1 month, and 2 months using a monofilament evaluator, measuring the area of sensory deficit at 1 mm intervals. The conventional group served as a control, as this approach is not associated with mental nerve injury.

resultsBaseline sensation was normal in both groups. The mean patient age was 32.5 ± 8.9 years (53% female). Operative times were significantly longer in the transoral group. All 37 transoral patients experienced transient sensory disturbances immediately postoperatively. The area of sensory deficit decreased at 1 and 2 months compared with 1 week (p = 0.028), and 5 of 37 patients achieved complete recovery by 2 months, while the remaining patients demonstrated progressive reduction in affected area. No sensory changes occurred in the conventional group at any time point.

conclusionsTransoral endoscopic thyroidectomy within a defined safety zone induces early transient sensory disturbances that improves or resolves by 2 months postoperatively. These findings support its use as a safe, cosmetically superior alternative to conventional thyroidectomy, with minimal long-term compromise to mental nerve integrity.

Indexed as

LipNatural Orifice Endoscopic SurgeryPostoperative ComplicationsSensation DisordersThyroid DiseasesThyroidectomyAdultChinFemaleHumansMaleMiddle AgedProspective StudiesYoung AdultCosmetic outcomesEndoscopic surgeryMental nerve injurySensory changesTransoral thyroidectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.