Application of contrast-enhanced ultrasound combined with ultra-high-frequency ultrasound in lymphaticovenous anastomosis.

Xing Huang, Yuanyan Tang, Zhongzeng Liang, Jia Zhu, Xiaoting Yu, Caigang Liu, Zhengren Liu

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

From Failure to Flow: Indocyanine Green Improves Preoperative Mapping for Lymphaticovenular Anastomosis After Negative Contrast-enhanced Ultrasonography.Plastic and reconstructive surgery. Global open · 2026
Article

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5 · Who and what money

Authors and funding

7 authors.

Xing Huang *Department of Ultrasound Medicine, Affiliated Hospital of Guangdong Medical University, Guangdong, China.

Yuanyan Tang *Nanchang University, Nanchang, China.

Zhongzeng Liang *Department of Breast Surgery, Affiliated Hospital of Guangdong Medical University, Guangdong, China.

Jia ZhuDepartment of Breast Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Xiaoting YuDepartment of Breast Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Caigang LiuDepartment of Oncology, Shengjing Hospital of China Medical University, Shenyang, China.

Zhengren LiuDepartment of Breast Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China. Lzr0926@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preoperative identification of functional lymphatic vessels (LVs) and accurate measurement of their internal diameters can facilitate lymphaticovenous anastomosis (LVA). However, current single imaging methods cannot accurately measure LVs internal diameters while locating functional LVs. This study aims to demonstrate the accuracy and effectiveness of combining contrast-enhanced ultrasound (CEUS) with ultra-high-frequency ultrasound (UHFUS) for precisely locating functional LVs and measuring internal diameters. 24 patients with secondary upper or lower extremity lymphedema were included in this retrospective study, who underwent three localization methods respectively: CEUS combined with UHFUS (Group A), CEUS alone (Group B), and UHFUS alone (Group C). 24 patients were all female (mean age, 61.9 ± 7.1 years [SD]). Compared with UHFUS, CEUS can locate more functional LVs more quickly (3.00 (2.00,3.00) number vs. 5.88 ± 1.25 number, P < 0.001

Indexed as

Anastomosis, SurgicalContrast MediaLymphatic VesselsLymphedemaAgedFemaleHumansMiddle AgedRetrospective StudiesUltrasonographyContrast MediaContrast-enhanced ultrasoundContrast enhanced ultrasound combined with ultra-high frequency ultrasoundLymphaticovenous anastomosisUltrahigh-frequency ultrasonographic

Identifiers

PMID41326622

DOI10.1038/s41598-025-30578-1

PMCPMC12783598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.