ArticleNature ecology & evolution2026
Core rumen microbes are functional generalists that sustain host metabolism and gut ecosystem function.
Article in Nature ecology & evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Next-generation probiotics and microbiome-based therapeutics highlighting Akkermansia muciniphila and Amuc_1100.World journal of microbiology & biotechnology · 2026Review
- Microbial DNA methylation links rumen transcriptional activity to methane emission divergence in dairy cows.iMeta · 2026Article
- Dietary Hydroxy-Selenomethionine Improves Antioxidant Status and Reduces Somatic Cell Count in Dairy Cows: Multi-Omics Insights into Rumen Microbiota and Metabolic Profiles.Antioxidants (Basel, Switzerland) · 2026Article
- Article
- Article
- Multi-omics analysis of soy isoflavone-induced responses in rumen fermentation, endocrine status and milk production in cows with varying milk yields.Journal of animal science and biotechnology · 2026Article
- Community context reshapes microbial proteomes and reduces functional overlap.Nature microbiology · 2026Article
- Rumen Microbiome Development in Lambs Following Maternal and Early-Life Prebiotic Mannan-Rich Fraction (MRF) Supplementation.Animals : an open access journal from MDPI · 2026Article
- Cornus officinalis extract modulates rumen microbiome and growth of lambs fed a high-concentrate diet.AMB Express · 2026Article
- Ruminosignatures associated with methane emissions and feed efficiency across geographies and cattle breeds.The ISME journal · 2026Article
- Intricate microbiome differences observed in lactating cows across methane intensity phenotypes.ISME communications · 2026Article
- Variation in zoo diets, offerings of leafy browse, and body condition scores in Matschie's tree kangaroos (PeerJ · 2026Article
- Rumen mycobiome dynamics and dairy productivity: functional contributions of fungi to milk yield in bovine ruminants.Frontiers in fungal biology · 2026Review
- BileActome reveals community-assembled bile acid metabolism in the rumen microbiome.ISME communications · 2026Article
- Effects of α-terpineol and 1,8-cineole fromFrontiers in veterinary science · 2026Article
- Distinct Rumen Microbial Features and Host Metabolic Responses in Three Cervid Species.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Some microbes persist across diverse gut microbiomes, raising the question of what features define these core taxa and allow them to persist across hosts. Using the rumen microbiome as a model system, we show that core microbes exhibit distinct attributes of ecological generalists, including greater strain variability and broader functional capacity, linked to larger genome sizes. By analysing ~3,000 genomes of core and non-core microbes and metabolically measuring their functional attributes with both biochemical assays and untargeted/targeted metabolomics, we find that these traits enable core microbes to be metabolically independent while also supporting non-core microbes and the host. Core taxa produce essential metabolites, such as amino acids and vitamins, and encode fibre-degrading enzymes crucial for host nutrition. Additionally, they engage in cross-feeding, providing non-core microbes with vital nutrients. This independence positions core microbes as foundational pillars of gut ecosystem stability, and influencing these microbes could modulate microbiome functionality and ruminant host metabolism, with possible downstream consequences for food security and environmental sustainability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.