Evidence map›Paper›PMID 41326593›Full record

SynthesisScientific reports2025

Evaluating oncoplastic breast-conserving surgery: oncological safety, risks, and satisfaction-a systematic review and meta-analysis.

Loretta Enikő Nyirády, András Czébely-Lénárt, Jakub Hoferica, Péter Hegyi, Péter Fehérvári, Péter Nyirády, Péter Riesz, Nándor Ács, Attila Szijártó, Zoltán Klárik

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Beyond survival: reconstructing body image and femininity after breast cancer.Revista da Associacao Medica Brasileira (1992) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Loretta Enikő NyirádyCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
András Czébely-LénártCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Jakub HofericaCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Péter FehérváriCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Péter NyirádyCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Péter RieszCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Nándor ÁcsCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Attila SzijártóCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Zoltán KlárikCentre for Translational Medicine, Semmelweis University, Budapest, Hungary. klarik.zoltan@semmelweis.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncoplastic breast-conserving surgery (OBCS) comprises diverse techniques aimed at enhancing aesthetic outcomes and safety in breast cancer treatment. However, a knowledge gap exists in understanding the comprehensive assessment of safety factors and satisfaction rates associated with OBCS techniques. This systematic review and meta-analysis aim to compare volume displacement (VD) and volume replacement (VR) techniques concerning oncological safety, complication rates and patient satisfaction. A systematic literature search was conducted in three databases-PubMed, Embase, and Cochrane Library (CENTRAL)-up to November 2023. Original articles with quantitative satisfaction rates, recurrence, re-excision, margin status, and complications (hematoma, seroma, wound infection, fat necrosis). The systematic search identified 17,374 records, with 80 eligible studies and 46 providing quantitative data. Results showed comparable oncological safety between VD and VR techniques, including similar recurrence (Prop: 0.02; CI 0.02-0.03) and re-excision rates (Prop: 0.05; CI 0.04-0.07). VR techniques had a higher incidence of fat necrosis (Prop: 0.07; CI 0.04-0.12). Overall satisfaction was high (Prop: 0.83; CI 0.78-0.87), with VD yielding the highest satisfaction (Prop: 0.93; CI 0.85-0.97). Oncoplastic breast-conserving surgery emerges as a successful approach for treating early-stage breast cancer, characterized by low associated risks and high satisfaction rates.

Indexed as

Breast NeoplasmsMammaplastyMastectomy, SegmentalPatient SatisfactionFemaleHumansNeoplasm Recurrence, LocalPostoperative ComplicationsTreatment OutcomeOncoplastic breast-conserving surgery (OBCS)SafetySatisfactionVolume displacement (VD)Volume replacement (VR)

Identifiers

PMID41326593
PMCPMC12775384

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.